^m'A0£]\m&v^'}  Minutes  °f  the  Pharmaceutical  Meeting.  239 
of  live  weight  was  found  to  be  fatal.  After  48  hours,  the  entrails 
were  divided  into  five  parts,  and  each  part  digested  several  times  at 
6o°  with  twice  its  weight  of  alcohol,  and  the  extract  concentrated 
nearly  to  dryness.  The  residue  was  taken  up  with  water,  and 
shaken  several  times  with  ether  in  order  to  extract  fatty  substances 
The  aqueous  solution  was  precipitated  with  basic  lead  acetate, 
filtered,  the  lead  removed  as  sulphide,  the  liquid  again  filtered, 
evaporated  to  dryness,  and  the  residue  finally  extracted  with  a  little 
absolute  alcohol,  in  which  the  ecgonine  exists  as  acetate  and  was 
readily  detected.  The  alkaloid  was  found  in  the  heart,  blood,  lungs, 
liver,  brain  and  spinal  cord. 
Ecgonine  Salts. — (C9H15N03)2Mg-[-3  i^H20,  very  hygroscopic 
plates,  soluble  in  water,  and  alcohol,  insoluble  in  ether,  melting  at 
1900.  (C9H15N03)2Ca  is  soluble  in  water  and  alcohol,  insoluble  in 
ether.  C9H15NOsAg,  orange-colored,  decomposing  readily  when 
exposed  to  the  light.  Ecgonine  -acetate,  C9H15N03,C2H402  -f 
2*^H20,  needle-like,  hygroscopic  crystals,  melting  at  1960,  very 
soluble  in  water  and  alcohol,  insoluble  in  ether. 
MINUTES  OF  THE  PHARMACEUTICAL  MEETING. 
Aprii,  16,  1891. 
The  seventh  of  the  present  series  was  held  this  day  ;  on  motion  of  Mr.  Wm. 
B.  Webb,  Mr.  Wm.  B.  Thompson  was  called  to  the  chair. 
The  minutes  of  the  last  meeting  were  read  and  no  corrections  being  required 
they  were  approved. 
The  secretary  read  the  formulas  for  Goddard's  astringent  gargle,  placed  in 
his  hands  by  Wm.  B.  Webb  and"  L.  C.  Funk,  both  are  known  to  have  been 
directed  by  the  late  Dr.  Paul  B.  Goddard. 
Fol.  rosae  rub.,   3 ii 
Aquae  bullientis,   f  il v 
Acidi  sulphurici  diluti,   f  o  ss 
Infuse,  when  cold,  strain  and  add  : 
Mel.  despumati,   f  Jfj 
Acidi  tannici,   ^  ii 
Aluminis,   3  i  j 
Spts.  vini  rectif,    f  3  vi 
Aqua  rosae,   f  3  vi 
M. 
The  other  formula  contains  pomegranate  rind  in  place  of  tannin,  but  this  is 
preferable. 
