7 
THE  AMERICAN 
JOURNAL  OF  PHARMACY. 
OCTOBER,  i8gi. 
DEPOSIT  FROM  TINCTURA  SANGUINARY. 
By  Frederick  Krauss. 
It  is  a  well-known  fact  that  tincture  of  sanguinaria,  U.  S.  P,, 
when  kept  for  a  few  weeks,  deposits  on  the  sides  of  the  containers,, 
a  reddish  film  of  what  seems  to  be  a  resin.  No  variation  of  the 
menstruum  seems  to  prevent  this.  It  does  not  interfere  with  the 
clearness  of  the  tincture,  but  merely  gives  the  shop  bottle  a  bad 
appearance,  after  a  quantity  of  the  tincture  has  been  taken  out  in 
the  routine  of  business. 
It  can  readily  be  removed  with  a  solution  of  NaOH  or  of  KOH. 
Ammonia  has  but  little  effect  upon  it.  The  fixed  alkali  liquids 
dissolve  only  a  small  proportion  of  the  deposits,  the  remainder 
being  removed  in  the  state  of  insoluble  powder. 
I  removed  a  quantity  of  this  resin  from  several  bottles  with  the 
aid  of  solution  of  NaOH.  Throwing  the  mixture  upon  a  plain, 
white  filter,  I  washed  it  first  with  water  (in  which  the  powder  is 
entirely  insoluble),  then  with  water  containing  a  small  quantity  of 
HC1.  Finally,  it  was  again  washed  with  pure  water  until  washings 
gave  no  reaction  to  test-solution  of  AgN03.  The  residue  was 
then  allowed  to  dry. 
It  forms  a  reddish-black,  somewhat  glistening,  resinous  powder, 
very  slightly  soluble  in  ether  and  alcohol.  It  is  more  soluble  in 
chloroform  and  spirit  of  chloroform,  the  former  making  a  deep  red 
solution,  whereas  the  latter  made  a  light  red  solution.  The  chloro- 
form is  of  course  the  solvent  in  both  cases.  The  resin  is  insoluble 
in  benzin,  burns  without  melting  with  a  bright  white  light,  and 
(473) 
