AmFeb.!'i8P9aarm'.!  Additional  Notes  on  Scopola  Carniolica.  107 
Passing-  now  to  a  description  of  the  Scopola  carniolica,  the 
dark  line  under  the  epidermis  is  narrower  and  less 
colored  than  that  of  belladonna.  The  entire  bark  is  not  so 
thick;  also,  the  vascular  bundles  are  neither  so  large  nor  so 
numerous,  and  the  bundles  of  raphides  are  less  bold  than  in 
the  belladonna  root.  In  fact,  much  the  same  tissues  are 
present,  but  less  pronounced  than  in  belladonna.  The  starch 
grains  also  are  smaller,  the  typical  grains  being,  as  in  bella- 
donna, muller-shaped,  but  there  is  a  large  number  which  it 
is  difficult  to  assign  to  any  well-defined  type  of  starch  grains. 
Very  minute  details,  when  they  do  not  serve  to  elucidate 
any  point  in  this  investigation,  have  been  avoided.  On  the 
whole  it  will  be  evident  from  this  histological  interpretation, 
that  there  seems  a  close  alliance  in  anatomical  structure 
between  the  rhizome  of  Scopola  carniolica  and  the  root  of 
Atropa  Belladonna. 
ADDITIONAL  NOTES  ON  SCOPOLA. 
By  John  M.  Maisch. 
As  a  supplement  to  the  highly  valuable  information  con- 
tained in  the  foregoing  paper,  the  following  historical  and 
pharmacognostical  notes  will  be  found  of  interest. 
Wittstein,  in  Handworterbnch  der  Pharmakognosic,  1882,  p. 
787,  writes  that  "  Matthiolus  discovered  this  plant  in  the  six- 
teenth century  near  Gorz,  and  also  figured  it,  but  it  seems  to 
have  been  forgotten,  until  Scopoli  (t  1 788)  found  it  again  near 
Idria.  .  .  .  Wier's  experiments  with  the  plant  as  a  remedial 
agent  received  little  attention.  In  more  recent  times  Dr.  Lip- 
pich,  of  Padua,  again  used  the  undoubtedly  very  active  plant  in 
such  diseases  which  have  thus  far  been  usually  treated  with 
belladonna." 
Schroff  {Pharmacognosies  edit.  1869,  p.  299)  states  that  "the 
plant  which  grows  near  Idria,  Laibach,  in  Hungary,  etc.,  has 
recently  been  again  more  frequently  employed,  particularly 
the  leaves,  herba  scopolinse,  and  the  root,  radix  scopolinae. 
.  .  .  The  rootstock  is  almost  horizontal,  0-026-0-04  m.  thick, 
of  a  whitish  color,  in  some  places  thickened,  almost  jointed, 
has  few  ambulations,  produces  upon  a  protuberance  occasion- 
