Am.  Jour.  Phai-m. 
April,  1890. 
Tincture  of  Musk. 
167 
The  portions  that  were  dissolved  by  petroleum  ether  left,  after 
spontaneous  evaporation,  a  crystalline  fat.  This  was  treated  with 
absolute  alcohol,  then  the  melting  points  of  both  were  taken ;  the 
fats  melted  at  400  C. 
After  treating  the  alcoholic  extract  with  water,  it  was  shaken 
with  ether,  then  separated  and  put  in  a  vacuum  sflask  and  evapo- 
rated to  dryness,  the  residue  taken  up  with  water  and  again  shaken 
with  ether ;  this  process  was  repeated  several  times  to  purify  the 
tannin.  The  tannins,  with  gallotannic  acid,  were  treated  with  the 
following  reagents  : 
Ferric  chloride, 
Tannin  of  Kr. 
Gallotannin.  triandra. 
deep  blue  pre-    olive  green  pre- 
cipitate, 
no  change, 
Ferrous  sulphate,    .  . 
Ferric  acetate,   bluish-black 
precipitate, 
Ivead  acetate,   fl.es  h-c  o  1  o  r 
precipitate, 
Ammonium  hydrate  and 
Iodine  solution,  .  .  red  color, 
Ferricyanide  Potass,  and 
Ammonium  hydrate,  .  red  color, 
Fehling's  solution,     .  .  reduced, 
cipitate, 
no  change, 
bluish-  green 
precipitate, 
flesh-color  pre- 
cipitate, 
red  color, 
red  color, 
reduced, 
Tannin  of  Kr. 
argentea. 
olive  green  pre- 
cipitate, 
no  change, 
olive  precipitate. 
flesh-color  pre- 
cipitate. 
red  color. 
red  color, 
reduced. 
From  these  experiments,  it  is  concluded  that  the  Krameria 
argentea,as  found  in  this  market,  is  a  little  lower  in  tannin  strength, 
as  well  as  in  the  other  constituents,  when  compared  with  the  true 
rhatany. 
The  properties  of  the  constituents  in  the  two  drugs  appear  to  be 
the  same. 
TINCTURE  OF  MUSK. 
By  Geo.  M.  Beringer,  Ph.G. 
Read  before  the  Philadelphia  College  of  Pharmacy  at  the  Pharmaceutical  Meeting, 
March  18. 
The  U.  S.  Pharmacopoeia  directs  that  Tincture  of  Musk  should  be 
made  of  10  parts  of  grain  musk  extracted  with  dilute  alcohol  to  yield 
IOO  parts  of  tincture. 
The  officinal  musk  is  pure  grain  musk,  which  in  recent  years  has 
ranged  in  price  from  $20  to  #35  per  oz.,  making  a  tincture  prepared 
by  this  process  cost  from  $30  to  $50  per  pint.    The  U.  S,  Dis- 
