182 
Cod  Liver  Oil  Emulsion. 
Am.  Jour.  Pharm. 
April,  1890. 
alone  merits  the  favor  of  ophthalmologists.'*  Nouveaux  Rem., 
March  8. 
Solubility  of  Caffeine  with  Antipyrin. — M.  Crinon  reports,  as 
a  result  of  recent  experiments  made  by  him,  that  by  adding  to 
caffeine  an  amount  of  antipyrin  slightly  in  excess  of  its  weight  it 
becomes  perfectly  soluble  in  water  without  the  aid  of  heat.  With 
heat  he  dissolved  50  cgm.  of  caffeine  in  10  gm.  of  distilled  water 
after  adding  75  cgm.  of  antipyrin,  and  the  solution  remained  limpid. 
The  author  adds  that  if  the  caffeine  be  prescribed  for  neuralgia  or 
hemicrania,  the  antipyrin  associated  with  it  will  aid  in  producing 
the  desired  effect. 
Panbotano  as  a  Substitute  for  Sulphate  of  Quinine.  —  At 
a  recent  meeting  of  the  French  Academy  of  Medicine,  Professor 
Dujardin-Beaumetz  stated  that  he  had  received  form  M.  Valude,  of 
Vierzon,  a  paper  relating  to  a  new  specific  for  the  fever  and  other 
symptoms  of  paludism.  This  medicament  consists  of  the  bark  of 
the  panbotano,  which  is  a  leguminous  tree  (suborder  mimosed)  of 
Mexico,  isolated  plants  being  cultivated  in  some  parts  of  Europe. 
M.  Villejean  has  studied  the  bark  and  found  fatty  matters,  tannin, 
etc.,  but  no  alkaloid' or  glucoside.  M.  Valude  administered  panbo- 
tano bark  to  his  patients  in  form  of  an  alcoholic  tincture,  and  also  gave 
a  preparation  made  by  maceration.  He  preferred  the  latter,  which 
he  made  by  putting  70  gm,  of  bruised  bark  into  a  quart  of  water 
and  boiling  down  to  a  pint,  this  being  the  quantity  to  be  taken  in 
twenty-four  hours.  In  the  eight  paludic  cases  described  by  M. 
Valude  a  single  dose,  or,  at  most,  two  doses,  caused  the  disappear- 
ance of  well-defined  tertian  fevers. — Bull,  m'ed.;  Nouveaux  Rem.y 
March  8. 
COD  LIVER  OIL  EMULSION. 
By  Herbert  Graham,  Hospital  Steward,  U.  S.  A. 
Cod  liver  oil  emulsions,  in  various  forms,  are  preparations  which 
have  of  late  become  somewhat  popular.  I  express  no  opinion  what- 
ever on  any  of  these  preparations,  far  less  do  I  intend  to  individu- 
alize any  preparation  by  attempting  to  give  a  copy  of  the  formula. 
I  simply  recognize  the  unfortunate  necessity  which  sometimes  arises 
of  following  where  our  inclination  does  not  lead,  and  I  therefore  give 
a  formula  for  an  emulsion,  believing  it,  without  prejudice,  equal  to 
any  of  the  many  now  before  the  profession  and  the  public. 
