234 
Prickly  Ash  Bark. 
f Am.  Jour.  Pharm  .. 
I       May,  1890. 
•  Fusion  with  caustic  potassa  yielded  formic,  acetic,  butyric  and 
probably  all  the  acids  of  the  series  as  far  as  caproic.  None  of  the 
aromatic  class  of  bodies  could  be  identified  among  the  products. 
The  substance  melted  at  129-5°  C.  and  resolidified  to  a  crystalline 
mass  at  123°  to  125°  C. 
Combustion  gave  the  following  results  : 
I,     "1542  gm.  of  substance  yielded  -3931  gm.  C02  and  '0744  gm.  H20. 
II,    -2697       "           "          "        -6855       "       "  -1279  " 
III,     -1186       "           "          "       -3010       "       "  -0572  " 
In  percentages : 
1.            11.  in. 
C,  69^17        69-32  69-21 
H,                                    5'36           5'27  5-36 
O,  .  .  .  .  25-47         25-41  25-43 
Calculated  for 
Average.  (C20H21Os). 
C,  69-23  69-18 
H,  -     5'33  5 '37. 
O,  25-44  25-45 
IOO'OO  IOO'OO 
CHLORINE-DERIVATIVE. 
Several  grams  of  the  purified  crystals  were  dissolved  in  ether  and 
dry  chlorine  gas  passed  into  the  solution  until  precipitation  ceased. 
The  crystalline  powder  so  obtained  was  thoroughly  washed  with 
alcohol  to  free  it  from  adherent  chlorine  and  carefully  dried  over 
sulphuric  acid.  The  ethereal  liquid  was  shaken  with  water  which 
after  separation  was  found  to  contain  hydrochloric  acid.  The  ether 
on  evaporation  left  a  small  amount  of  an  amorphous  residue  which 
by  treatment  with  alcohol  yielded  more  of  the  crystalline  product. 
The  latter  melted  at  169-5°  C.,  with  evolution  of  hydrochloric 
acid. 
To  estimate  the  chlorine  -4524  gm.  of  substance  was  heated 
with  pure  calcium  carbonate  in  a  tube,  dissolved  in  dilute  nitric  acid 
and  precipitated  with  silver  nitrate.  This  yielded  -4871  gm.  of 
AgCl,  equivalent  to  26-63  Per  cent,  of  chlorine.  Assuming  that 
chlorine  replaces  an  equal  number  of  hydrogen  atoms  in  the  formula 
(C29H27Os)  this  would  indicate  the  replacement  of  five  atoms  (calcu- 
lated 26-27  Per  cent,  of  CI).  To  prove  the  correctness  of  this  result 
a  second  estimation  was  made  using  sodium  carbonate.    "3464  gm. 
