Ani.  Jour.  Pharm. ) 
June,  1890.  J 
■'Bark  of  Prinos  Verticillatus. 
275 
being  also  formed.  Strong  nitric  acid  changes  to  red-brown,  and 
after  about  5  minutes  causes  violent  effervescence,  a  disagreeable 
odor  being  given  off,  and  after  cooling  a  reddish-brown  semi-solid 
mass  is  left. 
Pumpkin  seeds  are  not  as  frequently  used  as  they  would  be  if 
they  could  be  administered  in  a  more  convenient  form.  The  intro- 
duction of  a  reliable  preparation  seems  desirable  and,  in  the  writer's 
opinion,  the  oleoresin  is  both  a  convenient  and  elegant  as  well  as 
effective  preparation.  It  can  be  easily  and  readily  prepared,  and  is 
probably  the  most  concentrated  liquid  form  of  pumpkin  seed  that 
can  be  devised.  It  may  be  given  in  doses  of  y2  to  I  y2  fluid-ounce, 
in  the  form  of  an  emulsion  flavored  with  aromatics. 
THE  BARK  OF  PRINOS  VERTICILLATUS. 
By  J.  Stewart  Smith,  Ph.G. 
From  an  Inaugural  Essay. 
On  exhausting  50  gm.  of  the  powdered  bark  with  different  sol- 
vents the  following  results  were  obtained : 
Per  Cent. 
Extract  with  petroleum  ether,   2*44 
stronger  ether,    2*07 
absolute  alcohol,    6*63 
water,  .  .  5*36 
(including  0*23  per  cent,  ash.) 
caustic  soda,                                       .   3^99 
(after  deducting  1-19  per  cent,  ash.) 
diluted  acid,   1  "79 
(after  deducting  2*05  per  cent,  ash.) 
chlorine  water,   1*96 
Soluble  organic  compounds,  Total,  24*24 
The  petroleum  extract  contained  a  little  volatile  oil.  The  ether 
extract  was  entirely  soluble  in  hot  alcohol,  had  a  neutral  reaction 
and  was  free  from  tannin.  The  alcohol  extract  was  entirely  soluble 
in  chloroform,  partly  soluble  in  water  with  a  faint  acid  reaction, 
contained  tannin,  reduced  Fehling's  solution,  and  gave  with  Mayer's 
reagent  a  slight  precipitate,  the  nature  of  which  was  not  ascertained. 
The  powdered  bark  contained  9  per  cent,  of  moisture  and  yielded 
4-3  per  cent,  of  ash.  See  also  analysis  of  the  bark,  by  L.  C.  Collier, 
in  Amek.  Jour.  Phar.,  1880,  p.  437. 
