3^4 
Varieties. 
f  Am.  Jour.  Pkarm. 
t        July,  1890. 
VARIETIES. 
Sozoiodol  in  Rhinology  and  Laryngology. — In  a  thesis  on  this  subject, 
Dr.  Stern  gives  the  therapeutical  indications  for  this  new  product.  He  is 
inclined  to  believe  that  its  action  depends  upon  the  grouping  of  the  component 
atoms.  Sozoiodoi  possesses  the  advantage  over  iodol  and  iodine  of  being  dis- 
engaged in  the  organism  in  its  organic  composition  and  not  in  the  form  of  an 
iodurite.  Furthermore,  the  action  of  the  sozoiodols  may  be  varied  in  their 
action  by  combining  them  with  various  metals.  The  following  are  the  indica- 
tions given  by  Stern  for  the  employment  of  the  various  preparations  of  sozoiodoi 
in  diseases  of  the  nose  and  larynx  : 
(1)  Sozoiodoi  of  sodium,  readily  soluble.  Indicated  in  all  cases  where  it  is 
desired  to  obtain  a  general  antisepsis  rather  than  a  local  antiseptic  action.  It 
is  also  used  in  all  cases  where  aqueous  solutions  are  employed. 
(2)  Sozoiodoi  of  potassium,  sparingly  soluble.  It  diminishes  the  secretions 
and  acts  as  a  desiccant — it  is  therefore  indicated  in  eczema.  It  is  usually 
employed  with  talc  in  the  proportion  1-5  or  1-6. 
(3)  Sozoiodoi  of  zinc  acts  locally  as  an  irritant  in  solutions  of  from  1-20  to 
1-50,  and  as  a  caustic  in  a  solution  of  1-5. 
(4)  Sozoiodoi  of  mercury  acts  locally  as  a  caustic,  even  in  a  solution  of  1-10. 
Miller  affirms  that  a  solution  of  2^  parts  in  100  of  this  solution  kills  the  acarus 
in  24  minutes. 
Good  results  have  been  obtained  in  atrophic  nasal  catarrh  (sozoiodoi  of  zinc 
1  part,  talc  10  parts),  in  hypertrophic  rhinitis  and  rhinopharyngitis  (sozoiodoi 
of  zinc  1  part,  talc  12  parts)  ;  good  effects  have  also  been  obtained  in  tubercular 
ulceration  of  the  pharynx  and  larynx,  and  in  syphilis  of  the  nose  and  larynx 
(zinc  salt  1-1 2,  or  mercuric  salt  1-20).  The  sozoiodoi  should  be  used  in  the 
form  of  powder,  unguent,  etc.  Where  use  is  made  of  aqueous  solutions  the 
sodium  salt  should  be  used. — D  Union  Med.  ;  four.  Amer.  Med.  Assoc.,  May 
24,  1890.    See  also  Amer.  Jour.  Pharmacy,  1888,  p.  621,  and  1889,  p.  17. 
The  Antiseptic  Power  of  Coffee. — Dr.  Liideritz  has  recently  made  a  number 
of  observations  on  the  destructive  power  of  coffee  upon  various  microbes.  He 
found  that  the  organisms  all  died  in  a  longer  or  shorter  period — e.  g.,  in  one 
series  of  experiments  anthrax  bacilli  were  destroyed  in  three  hours,  anthrax 
spores  in  four  weeks,  cholera  bacilli  in  four  hours,  and  the  streptococcus  of 
erysipelas  in  one  day.  It  was,  however,  remarkable  that  good  coffee  and 
bad  coffee  produced  precisely  similar  effects.  He  believes  that,  as  previous 
observers  have  suggested,  the  antiseptic  effect  of  coffee  does  not  depend  on  the 
caffeine  it  contains,  but  on  the  empyreumatic  oils  developed  by  roasting. — 
four.  Am.  Med.  Assoc.,  May  10. 
Iodoform  emulsion  has  been  much  employed  as  a  local  antiseptic  and  an 
antituberculous  remedy  by  Prof.  Billroth  and  others.  For  preparing  the  emul- 
sion, finely-powdered  iodoform  is  suspended  either  in  a  mixture  of  almond 
and  castor  oils,  or  in  olive  oil  and  glycerin,  or  in  glycerin  alone.  Moorhof 's 
formula  directs  iodoform  50,  glycerin  40,  distilled  water  10,  and  tragacanth 
0*30.  Billroth  found  a  10  per  cent,  emulsion  serviceable,  and  Jasinski  injected 
180  gm.  of  a  10  per  cent,  emulsion  at  once  without  observing  any  toxic  symp- 
toms.—^Jour.  Amer.  Med.  Assoc.,  June  10,  pp.  873,  874. 
