402  Gleanings  from  the  German  Journals.  {AmAS'i89oarm 
sample  of  antipyrine  put  up  in  a  metal  box  had  a  decidedly  reddish 
yellow  color  where  the  powder  came  in  contact  with  the  metaL 
Examination  of  the  sample  showed  it  to  answer  all  tests  of  purity 
excepting  the  color.  To  prevent  the  discoloration  the  powder  is 
recommended  to  be  put  in  glass  containers  or  transferred  to  such 
as  soon  as  received  by  the  apothecary. — Oesterr.  Ztschr.  f.  Pharm.y 
1890,  301. 
Eugenol  has  been  found  by  Pomeranz  to  be  a  constituent  of  oil  ot 
sassafras  although  in  small  quantity.  From  3  kilos  crude  sassafras 
oil  he  obtained  7  grams  of  a  phenol  boiling  at  246-2470  having  an 
eugenol  like  odor  and  which  by  analysis  and  conversion  into  the 
benzoyl-derivative  was  proven  to  be  identical  with  the  eugenol'  of 
the  oil  of  cloves. — [Monatsh.  d.  Chemie)  Apotheker  Ztg.>  1890,  345. 
Fluid  glycerin-soap.  500  gm.  olein,  100  gm.  alcohol  and  280  gm. 
potash  lye  (33^  per  cent.)  are  placed  in  a  flask  and  agitated  fre- 
quently while  warmed  in  a  steam-bath  for  one-half  hour,  a  solution 
of  50  gm.  potassium  carbonate  in  100  gm.  water  is  then  added  and 
the  heating  continued  until  a  portion  removed  is  perfectly  soluble 
in  water.  The  soap  is  next  dissolved,  with  heat,  in  1570  gm. 
glycerin,  set  aside  for  a  few  days  in  a  cool  place  and  filtered ;  the 
filtrate  can  be  perfumed  as  desired. — Pharm.  Ztg.,  1890,  386. 
Antipyrine  and  sodium  salicylate  have  frequently  been  noticed  to 
liquefy  if  the  powders  had  been  intimately  mixed  and  exposed  to  the 
atmosphere  for  a  short  time.  Prof.  Spica  (in  L'  Orosi  of  May,  1 890) 
finds  the  liquefaction  possible  only  in  moist  air  and  to  be 
attended  by  an  increase  in  weight,  and  after  careful  experiments 
states  that  no  chemical  change  takes  place.  The  hygroscopic 
sodium  salicylate  by  absorption  of  water  enables  the  antipyrine  to 
dissolve,  the  latter  being  more  soluble  than  the  sodium  salicylate. 
He  also  gives  a  method  for  obtaining  the  true  antipyrine  salicylate : 
100  parts  antipyrine  are  dissolved  in  a  rather  large  quantity  of  boil- 
ing water  and  73-4  parts  sodium  salicylate  added  in  small  portions  ; 
on  cooling  the  new  chemical  separates  in  crystals ;  they  have  the 
formula  CnH12N2OC7H603. — Pharm.  Ztg.,  1890,  386. 
Salipyrine. — The  publication  of  the  above  article  has  occasioned 
the  announcement  that  J.  D.  Riedel,  of  Berlin,  has  applied  for 
patents  in  various  countries  covering  the  manufacture  of  antipyrine 
salicylate,  to  be  known  as'"  Salipyrine  "  Riedel.  The  mode  of  pre- 
paration is  not  made  public,  but  it  is  stated  to  be  cheaply  made,  as 
