Am ' l^/Jm*™''} Assay iitg  Galenical  Preparations  of  Opium.  407 
Decbr.,  1889)  as  a  dressing  for  various  ulcers,  the  application  being 
renewed  every  day  or  two.  It  effects  healthy  granulation  and 
cicatrization  without  producing  toxic  symptoms. 
Antiseptic  Mouth  Wash. — A  formula,  published  in  Therap. 
Monatsh.,  Febr.,  1890,  directs  saccharin  i-o,  sodium  bicarbonate 
0-5,  and  alcohol  1 00  gm.,  with  2  drops  of  oil  of  peppermint.  For 
use  add  a  teaspoonful  to  a  small  glassful  of  water. 
Tincture  of  Helianthus  annuus  is  stated  by  Dr.  Maminoff  to  have 
given  excellent  results  in  the  treatment  of  intermittent  fever  of 
children.  It  was  prepared  from  the  fresh  flowers  and  bark  of  the 
plant,  of  the  strength  1:5.  The  dose  was  10  to  25  drops  three  or 
four  times  daily.  The  children  took  the  medicine  readily.  No 
secondary  effects  were  observed.* — Les  Nouv.  Reniedes,  1890,  p.  78. 
Carbolated  oil,  prepared  of  carbolic  acid  1  part,  and  olive  oil  1 5 
parts,  is  a  very  efficient  remedy  in  itch,  according  to  the  experience 
of  Dr.  F.  Trisilian. — Les  Nouv.  Remedes,  1890,  p.  225. 
Administration  of  Naphthalin. — Owing  to  its  insolubility  in  water 
and  weak  alcoholic  liquids,  Tichborne  advises  it  to  be  dissolved  in  a 
fixed  oil,  and  this  solution  to  be  converted  into  an  emulsion  in  the 
usual  manner.  To  obtain  it  in  powder,  naphthalin  is  best  precipi- 
tated by  pouring  its  solution  in  strong  alcohol  or  acetic  acid  into 
cold  water,  collecting  the  precipitate,  washing  it  well  with  water, 
and  drying  at  a  gentle  heat. 
SHORT  METHODS  FOR  ASSAYING  GALENICAL 
PREPARATIONS  OF  OPIUM, 
AND  A  REVIEW  OF  FLUCKIGEr's  METHOD  FOR  OPIUM  ASSAY  COMPARED 
with  squibb's  and  stillwell's. 
By  J.  B.  Nagelvoort. 
"The  presence  of  sugar  makes  the  estimation  of  alkaloids  more  difficult." — 
Dieter ich  and  others. 
"  To  separate  in  one  operation  the  whole  of  the  morphine  in  a  perfectly  pure 
•state  is  an  impossibility." — Digest  of  Criticisms  on  the  U.S. P.,  1890,  III,  p.  319. 
Opium  assays  are  always  interesting,  inasmuch  as  opium  is  one 
of  our  few  reliable  remedies,  and  inasmuch  as  a  large  amount  of  capi- 
tal may  be  involved  in  morphine  determinations.  A  successful  experi- 
ment to  shorten  the  time  of  assay  is  a  benefit  for  the  manufacturing 
