496  AristoL  {Am-fcSTm- 
mouth  to  the  orbit,  the  lower  eyelid  being  completely  destroyed. 
The  healing  action  in  this  case  was  at  once  evident,  and  in  five  or 
six  days  the  wound  was  becoming  covered  with  a  firm  cicatrix,  and 
at  the  time  the  patient  was  presented  to  the  Society,  after  use  of 
the  remedy  for  three  weeks,  only  very  small  wounds  remained.  Dr. 
Brocq  has  also  had  most  gratifying  results  in  other  cases  in  which 
he  has  used  the  drug,  especially  ulcers  of  the  legs  and  ulcerated 
gummata. 
Dr.  Gaudin3  reports  cases  of  psoriasis,  ulcers,  eczema,  and  chancre, 
in  which  he  has  used  the  drug  with  most  excellent  results ;  in  one 
'  case  of  ulcer  of  the  leg,  in  which  he  made  comparative  experiments 
with  iodoform  and  hydrarg.  biniodide,  the  result  with  aristol  far 
exceeded  that  with  the  other  drugs.  In  all  his  cases  the  marked 
property  of  the  drug  in  favoring  cicatrization  was  most  striking. 
Dr.  Gaudin  applied  the  drug  either  dissolved  in  ether  or  collodion, 
or  as  a  dusting  powder. 
Dr.  Hughes4  has  found  the  drug  of  much  service  in  all  those 
forms  of  rhinitis  associated  with  a  dryness  of  the  mucous  surface,  or 
in  which  there  is  a  tendency  for  the  secretion  to  undergo  decom- 
position. He  reports  twenty-one  cases  in  which  he  has  tried  the 
remedy,  and  in  all  the  result  was  most  satisfactory ;  in  two  cases  of 
specific  ozcena  the  disappearance  of  the  fcetor  and  the  healing  was 
very  rapid. 
Dr.  Lbwenstein5  has  treated  four  cases  of  ozcena  with  the  drug, 
and  reports  most  favorably  on  its  effects  in  one  case  of  specific  ozcena. 
In  addition  to  insufflation  of  the  drug  in  powder,  he  painted  the 
ulcerated  parts  with  a  solution  in  collodion  flexile.  He  speaks  very 
favorably  of  the  property  the  drug  has  of  forming  a  covering  over 
the  diseased  surface. 
Professor  Neisser6  has  made  experiments  on  the  action  of  aristol 
on  bacteria,  and  also  used  it  therapeutically  in  thirteen  cases  of 
lupus  exulcerans,  in  which  he  found  it  of  great  service.  In  lichen 
rubra,  soft  chancre,  and  gonorrhoea  the  results  were  not  satisfactory. 
Dr.  Schirren7  has  treated  ten  cases  of  psoriasis  of  various  forms, 
8  Journal  des  Malad.  Cutan.  et  SyphiL  de  M.  le  Dr.  Fournier,  1890. 
4  Deutsche  med.  Wochenschr.,  1890,  Nos.  18  and  19. 
5  Internat.  klin,  Rundschau,  Wien,  Mar.,  1890. 
6  Berlin  klin.  Wochenschr.,  1890,  No.  19. 
7  Berlin  klin.  Wochenschr.,  1890,  No.  11. 
