544 
Varieties. 
Am.  Jour.  Pharm. 
Oct.,  1890. 
Atropine  as  an  antagonist  to  chloroform  was  recommended  many  years  ago 
by  Albertoni,  and  his  results  were  recently  confirmed  by  others.  Dr.  I;.. 
Vincini  {Centralbl.  f.  Klin.  Med.)  reports  success,  only  failing  after  the 
administration  of  such  large  doses  of  chloroform  as  to  produce  coagulation  of 
the  heart  tissue.  As  a  prophylaxis  in  chloroform  anaesthesia,  the  subcutaneous 
injection  of  o-oo2  gm.  of  atropine  is  recommended,  about  one-half  that  quan- 
tity for  children,  and  double  the  dose  in  cases  of  emergency. 
The  Inefficiency  of  Sand  Filters. — Drs.  Frankel  and  Piefke,  of  Berlin,  have 
recently  made  an  exhaustive  study  on  the  filtration  of  drinking-water  through 
sand  {Zeitschrift  fi'ir  Hygiene,  No.  i,  1890).  Their  experiments  conclusively 
prove  that  the  danger  of  infection  from  impure  water  is  only  slightly  reduced 
by  filtration  through  sand  ;  bacteria  passing  through  at  all  times,  but  in  larger 
numbers  just  after  the  filter  has  been  cleaned,  and  again  after  it  has  been  in 
use  for  some  time. — Med.  News,  May  10. 
