Am'jJu0ne,'wo3arm'}  Progress  in  Pharmacy.  285 
PROGRESS  IN  PHARMACY. 
A  QUARTERLY  REVIEW  OF  SOME  OF  THE  MORE  INTERESTING  ADVANCES 
IN  PHARMACY  AND  MATERIA  MEDICA. 
BY  M.  I.  WllvBSRT, 
Apothecary  at  the  German  Hospital,  Philadelphia. 
That  the  rate  of  increase  in  the  number  of  the  newer  remedies  is 
not  abating  is  evidenced  by  the  number  and  variety  of  names  that 
are  published  in  each  of  the  issues  of  the  different  pharmaceutical 
journals.  Owing  to  this  too  bountiful  supply  of  available  material, 
it  is  difficult  indeed  to  always  select  matter  of  permanent  value.  It 
is  evident,  therefore,  that  much  of  the  data  that  finds  its  way  into 
these  reviews  must  necessarily  be  of  a  more  or  less  ephemeral  char- 
acter ;  but  even  as  such  it  has  its  value  in  illustrating  the  trend  of 
the  work  on  these  new  remedies.  It  will  be  remembered  that  several 
years  ago  inventive  fancy,  or  ideas,  appeared  to  concentrate  on 
organic  silver  compounds ;  later  they  were  concentrated  on  compli- 
cated preparations  of  arsenic,  while  at  the  present  time  quinine 
compounds  appear  to  be  in  favor. 
In  a  recent  number  of  American  Medicine  a  number  of  these  newer 
quinine  compounds  are  mentioned  {American  Med.,  May  3,  1902, 
page  760),  among  them : 
Aristochin,  said  to  be  diquinine  carbonate,  occurs  as  a  white, 
almost  tasteless  powder,  freely  soluble  in  dilute  hydrochloric  acid, 
and  is  said  to  be  qualitatively  and  quantitatively  the  equivalent  of 
quinine  hydrochlorate. 
Chinaphenin,  combination  of  quinine  and  phenetidin.  According  to 
the  Pharmaceutische  Centralhalle ,  1903,  p.  81,  this  is  the  quinine  car- 
bonic acid  ester  of  phenetidin,  and  occurs  as  a  light,  white,  tasteless 
powder,  freely  soluble  in  alcohol,  ether,  chloroform  and  dilute  acids. 
Used  as  an  antipyretic,  analgesic  and  anti-neuralgic  in  doses  of 
from  0  5  to  ro  gramme. 
Euquinine. — This,  the  carbonic  ethylester  of  quinine,  is  also  a  white 
powder,  almost  insoluble  in  water,  but  easily  dissolved  in  alcohol 
or  ether.  It  has  the  same  properties  and  may  be  given  in  the  same 
doses  as  chinaphenin. 
Saloquinine  or  salochinin  has  been  noted  in  this  journal  (Amer. 
Jour.  Pharm.,  1902,  p.  445).  It  is  the  salicylic  acid  ester  of  qui- 
nine, and  is  given  in  doses  of  from  i*oo  to  2*oo  grammes. 
