336 
B  as  ham's  Mixture. 
j  Am.  Jour.  Pharm. 
(     August.  1903. 
Hospital,  by  whom  it  was  given  to  Edwin  M.  Boring,  of  Philadel- 
phia.   It  is  as  follows  : 
Tr.  ferric  chloride   3     f  3 
Ac.  acetic  diluted   4     f  3 
Sol.  ammon.  acetate   3/4  f% 
Curacoa  cordial   1 
Syrup  1   1  fg 
Water  sufficient  to  measure   8     f  § 
Basham's  Mixture  was  first  officially  recognized  by  the  U.S.  Phar- 
macopoeia 1880,  under  the  name  of  "  Mistura  Ferri  et  Ammonii 
Acetatis,"  and  the  following  was  the  equivalent  formula  of  the 
"  parts-by-weight  "  formula: 
Tr.  ferric  chloride   83  m. 
Ac.  acetic  diluted   2  f  3 
Sol.  ammon.  acetate   14  f  3 
Elixir  orange   6  f  3 
Syrup  .  .   1  il 
Water  sufficient  to  measure  '  8f^ 
In  the  1890  U.S. Pharmacopoeia  the  title  was  changed  to  "Liquor 
Ferri  et  Ammonii  Acetatis,"  and  the  equivalent  formula  of  the 
metric  formula  given  is: 
Tr.  ferric  chloride   77  m. 
Ac.  acetic  diluted    115  m. 
Sol.  ammon.  acetate   12*8  fg 
Aromatic  elixir   6*4  f  3 
Glycerin   7'68f3 
Water  sufficient  to  measure   8  f  3 
These  formulas  have  been  given  at  some  length  for  the  purpose 
of  showing  the  radical  departure  of  the  Pharmacopoeia  from  the 
formulas  originally  used  and  upon  which  the  reputation  of  the  prep, 
aration  was  first  established.  Practically  the  older  formulas  repre- 
sented in  each  dessertspoonful  of  the  mixture,  5  minims  of  tincture 
of  iron  and  60  minims  of  solution  of  ammonium  acetate ;  the 
official  formula  represents,  in  the  same  quantity,  but  2j£  minims  of 
tincture  of  iron  and  24  minims  of  solution  of  ammonium  acetate. 
As  the  usual  dose  of  Basham's  Mixture  is  from  a  dessertspoonful 
to  a  tablespoonful,  and  as  the  usual  dose  of  tincture  of  iron  is  from 
5  to  10  minims,  and  of  solution  of  ammonium  acetate  from  1  to  2 
fluidrachms  or  more,  the  usual  dose  of  the  mixture  should  represent 
the  usual  doses  of  tincture  and  solution,  especially  as  the  iron 
salt  used  is  chemically  changed  from  a  stronger  into  a  weaker 
