^p/ember^igos0'}    American  Pharmaceutical  Association.  429 
Journal,  1902,  p.  507)  confirm  these  statements  by  experimental 
evidence.  They  further  state,  however,  that  they  have  found  no 
evidence  of  the  toxic  effects  as  stated  by  Ebert,  whereupon  Mr. 
Ebert  questions  what  this  statement  means,  as  his  claim  has  been  all 
along  that  narcotine  is  non-toxic. 
Acetic  Acid  as  a  Menstruum  for  Making  Fluid  Extracts. 
By  J.  Percy  Remington. 
In  this  paper  the  author-summarized  the  results  of  experiments 
during  the  past  few  years  in  the  manufacture  of  this  class  of  prepa- 
rations and  their  medical  properties.  Dr.  Kremers  asked  if  experi- 
ments had  been  made  to  determine  if  there  was  a  hydrolyzing 
action  of  the  acetic  acid  menstruums  on  the  principles  of  such  drugs 
as  hyoscyamus,  etc. 
A  New  Metric  Medicine  Glass. 
By  M.  I.  Wilbert. 
The  author  has  devised  a  conical  glass,  which  is  graduated,  in  such 
a  way  that  a  teaspoonful  is  equivalent  to  5  c.c;  a  dessertspoonful  to 
10  c.c.  and  a  tablespoon  to  15  c.c.  In  reply  to  the  statement  that 
physicians  should  write  their  prescriptions  in  the  metric  system,  as 
contended  by  one  of  the  speakers  discussing  this  paper,  Mr.  Smith 
said  that  while  physicians  may  write  their  prescriptions  in  the  metric 
system,  they  will  order  the  dose  in  teaspoons. 
On  the  Crystalline  Substances  of  Prickly  Ash  Bark. 
By  H.  M.  Gordin. 
The  author  has  isolated  the  crystalline  substances  from  both 
northern  and  southern  prickly  ash  barks.  The  method  of  isolating 
the  crystalline  principle  (xanthoxylin,  designated  very  happily  by  the 
author  as  xanthoxylin  N)  from  northern  prickly  ash  is  as  follows : 
44  Exhaust  the  powdered  northern  prickly  ash  with  benzine,  distill 
the  latter  off  and  take  up  the  oily  residue  with  a  mixture  of  alcohol, 
water  and  potassium  hydroxide  (for  ico  grams  oil  take  20  grams 
KOH,  20  c.c.  water  and  70  c.c.  alcohol).  Warm  the  mixture 
gently  about  10  minutes,  dilute  with  water  to  about  ten  times 
the  amount  of  oil  taken  and  pass  C02  into  the  mixture  till  the 
latter  commences  to  become  thick  and  change  color  from  green  to 
