462  Syrup  of  Calcium  Lactophosphate.      { A  ocSber.^fcf133' 
powder  which  is  to  be  sifted,  and  particularly  its  specific  gravity,  all 
have  a  bearing  in  influencing  the  drug  miller  to  seek  a  heavier  or 
lighter  gauge  wire  for  a  special  purpose,  but  there  is  no  reason  why, 
for  pharmaceutical  purposes,  a  standard  gauge  should  not  be  speci- 
fied in  the  Pharmacopoeia. 
SYRUP  OF  CALCIUM  LACTOPHOSPHATE.1 
By  Charges  H.  LaWall. 
In  September,  1901,  the  author  presented  a  paper  upon  the  sub- 
ject of  Easton's  syrup,  in  which  the  difficulties  attending  the 
preservation  of  this  preparation  were  obviated  by  a  simple  modifi- 
cation of  the  formula,  whereby  it  was  divided  and  the  concentrated 
solution,  or  glycerol,  held  in  readiness  to  mix  with  the  syrup  at  any 
time,  thus  insuring  an  unaltered  preparation. 
While  the  necessity  for  a  similar  change  in  the  formula  for  syrup 
of  calcium  lactophosphate  is  not  nearly  so  apparent  as  it  was  in 
the  former  case,  still,  it  is  believed  that  such  a  modification  would 
prove  of  benefit,  and  undoubtedly  it  affords  a  certain  convenience  in 
dispensing,  which  is  very  satisfactory  to  the  druggist,  while  it,  as  in 
the  former  case,  insures  the  freshness  of  the  preparation  at  the  time 
of  dispensing. 
Syrup  of  calcium  lactophosphate  does  not  have  the  same  ten- 
dency to  caramelization  that  Easton's  syrup  has,  but  it  does  undergo 
some  kind  of  a  decomposition  when  kept  in  stock  for  more  than 
a  very  few  weeks,  and  acquires  a  peculiar  disagreeable  odor — very 
much  unlike  the  freshly  made  preparation.  This,  I  believe,  is  partly 
due  to  the  small  amount  of  orange-flower  water  which  is  present 
(only  25  c.c.  in  1,000  c.c),  the  amount  being  scarcely  enough  to 
afford  the  characteristic  odor,  which  is  evidently  desired,  and  cer- 
tainly that  small  a  quantity  would  have  no  influence  on  the  flavor. 
A  far  better  plan  would  be  to  either  drop  the  orange-flower  water 
altogether,  or  else  add  enough  to  make  its  use  worth  while. 
With  the  view  of  overcoming  this  difficulty  the  following  formula 
was  tried  and  found  to  work  so  satisfactorily  in  actual  practice  that 
the  results  were  deemed  worthy  of  publication.    To  make  I, OOO  c.c. 
1  Read  at  the  annual  meeting  of  the  Pennsylvania  Pharmaceutical  Associa- 
tion, June,  1903,  and  contributed  by  the  author. 
