ON  THE  ROOT  OF  FRAZERA  WALTERI.  23 
Take  of  Extract  of  Belladonna, 
"  Conium, 
"  Hyoscyamus, 
"        Stramonium,  each 
Aqueous  Extract  of  Opium  3ii- 
Dissolve  the  extracts  in  a  little  boiling  water,  and  add 
Olive  oil,  Oiiss. 
Strain,  and  when  cool  add  the  same  proportion  of  oils  as  in  the 
preceding  formula. 
This  process  has  the  advantage  of  being  more  expeditious, 
and  furnishes  a  preparation  of  equal  strength  with  that  from  the 
recent  leaves. 
A  remedy  containing  the  same  ingredients,  and  made  in  a 
similar  manner,  substituting  Glycerine  for  the  Olive  Oil,  has 
been  prescribed  under  the  name  of  Baume  Anodyne  ;  as  an 
application  for  ear-ache,  which  the  pharmaceutist  is  frequently 
called  upon  to  furnish,  these  preparations  answer  an  admirable 
purpose,  being  both  prompt  and  effectual. 
ON  THE  HOOT  OF  FRAZERA  WALTERI. 
Br  W.  R.  Higinbothom,  of  Bermuda. 
(From  an  Inaugural  Essay.) 
The  Frazera  Walteri,  called  also  American  Columbo  and 
American  Gentian,  is  an  indigenous  plant  found  along  the  base 
of  the  Alleghany  mountains  in  the  southern  and  western  States, 
and  also  in  Arkansas  and  Missouri,  in  great  abundance.  The 
root  has  been  subjected  to  a  chemical  investigation,  with  results 
but  partially  satisfactory. 
The  infusion  has  a  bright  reddish  brown  color,  an  agreeable 
bitter  taste,  and  a  decided  acid  reaction.  Oxalate  of  ammonia 
causes  a  precipitate,  and  sesquichloride  of  iron  occasions  a 
greenish  black  color.  The  solutions  of  the  acetates  of  lead  and 
of  nitrate  of  mercury  immediately  coagulated  it.  Lugol's  solu- 
tion and  bichloride  of  mercury  no  change.  From  these  tests 
the  presence  of  lime,  an  organic  acid,  and  gummy  matter  is  in- 
ferred, whilst  starch  and  albumen  are  absent. 
An  ethereal  tincture  made  from  washed  ether  had  an  amber 
