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SYRUP  OP  IPECACUANHA. 
average  pressure  of  45  lbs.  The  cloves  are  put  in  the  still  un- 
ground,  which  is  found  preferable  to  grinding  them.  The 
yield  of  oil  is  about  16  per  cent,  on  the  average,  or  nearly  60 
lbs.  from  the  charge  of  350  pounds. 
ON  THE  FLUID  EXTRACT  AND  THE  SYRUP  OF  IPECACUANHA. 
By  William  Procter,  Jr. 
An  alcoholic  fluid  extract  of  Ipecacuanha  has  been  recom- 
mended by  the  Committee  of  the  College  of  Pharmacy,  as  a 
means  of  making  the  syrup.  This  extract  is  made  of  the  strength 
of  an  ounce  to  the  fluid  ounce  by  evaporating  the  tincture  made 
with  alcohol  -835  till  reduced  to  the  proper  strength.  This 
fluid  extract  contains  the  resin  of  the  ipecacuanha,  and  its 
odorous  fatty  matter  and  wax,  in  part.  When  such  fluid  ex- 
tract is  employed  to  make  the  syrup  by  simply  adding  it  to 
simple  syrup,  cold  or  hot,  a  cloudy  syrup  is  obtained,  which, 
while  it  is  efficient  and  keeps  well,  separates  by  standing,  and 
does  not  present  a  handsome  appearance.  With  a  view  to 
remedy  this  objection,  it  is  proposed  to  rid  the  fluid  extract  of 
all  matter  insoluble  in  cold  water,  so  that  when  added  to  simple 
syrup,  it  shall  produce  a  transparent  medicated  syrup. 
The  following  formula  is  recommended  : 
Take  of  Ipecacuanha,  in  fine  powder,  16  ounces,  (troy,) 
Alcohol, 
Water,  of  each  a  sufficient  quantity. 
Mix  the  Ipecacuanha  with  six  fluid  ounces  of  alcohol,  pack  it 
firmly  in  a  conical  percolator,  cover  it  with  a  disc  of  muslin, 
and  pour  on  alcohol  until  three  pints  have  nearly  passed,  or 
until  the  drug  is  exhausted.  Distil  off  the  alcohol  from  this  tinc- 
ture till  a  syrupy  residue  remains  ;  throw  this  into  a  pint  of 
water ;  boil  it  until  the  last  traces  of  alcohol  disappear,  the 
liquid  becomes  nearly  clear,  and  the  waxy  oleoresinous  matter 
separates,  and  adheres  to  the  vessel.  When  the  solution  cools 
filter  it  through  paper,  and  if  it  does  not  measure  eight  fluid 
ounces,  mix  the  residue  with  sufficient  water  to  make  that  measure, 
but  if  it  measure  more  evaporate  it  carefully  to  that  bulk.  To 
this  add  eight  fluid  ounces  of  alcohol,  and  mix. 
