Am.  Jour.  Pharm  > 
May,  1911.  / 
Petrox  Preparations. 
219 
PETROXOLINUM  lODI. 
Iodine  Petroxolin.       Iodine  Petrox  10  per  cent. 
Iodine    10  Gm. 
Oleic  Acid    40  Gm. 
Alcohol    20  Gm. 
Liquid  Petrolatum   23  Gm. 
Oil  of  Lavender  Flowers   2  Gm. 
Stronger  Ammonia  Water   5  Gm. 
Reduce  the  Iodine  to  a  coarse  powder  by  triturating  in  a  mortar 
and  transfer  it  to  a  suitable  flask,  add  the  Alcohol  and  then 
the  Oleic  Acid  and  agitate  the  contents  of  the  flask  until  the  Iodine 
is  dissolved;  now  add  the  Oil  of  Lavender  Flowers  and  the  Liquid 
Petrolatum  and  mix  the  liquids  and  finally  add  the  Stronger  Water 
of  Ammonia,  shaking  the  mixture  until  a  clear  solution  results. 
It  was  found  impossible  to  prepare  a  10  per  cent.  Iodine  Petrox 
by  simple  solution  in  the  liquid  Petroxolin.  By  improper  mixing 
there  results  another  difficulty,  namely,  the  separation  out  of  the 
iodine  as  a  salt,  and  this  is  a  difficulty  that  has  not  been  overcome 
by  some  of  the  manufacturers  of  the  proprietaries.  The  writers 
have  examined  several  bottles  of  one  manufacture  that  is  greatly 
prescribed  in  which  appeared  quite  heavy  crystalline  sediments  that 
proved  to  be  ammonium  iodide.  A  sample  made  by  the  proposed 
formula  has  now  been  kept  for  more  than  five  months  without 
sign  of  any  separation  of  crystalline  deposit. 
PETROXOLINUM  lODI  DILUTUM. 
Diluted  Iodine  Petroxolin.  Iodine  Petrox  5  per  cent. 
Iodine  Petroxolin    50  Gm. 
Liquid  Petroxolin    50  Gm. 
Mix  them. 
ALTERNATIVE  FORMULA. 
Iodine  in  coarse  powder   5  Gm. 
Liquid  Petroxolin    95  Gm. 
Dissolve  the  Iodine  by  agitation  with  the  Liquid  Petroxolin  in 
a  stoppered  bottle. 
An  assay  process  should  be  provided  for  the  Iodine  Petroxolins. 
The  Erganzungsbuch  zum  Deutschen  Arzneibuch  gives  a 
method  of  assay  which  should,  however,  be  thoroughly  tried  by 
competent  chemists  before  adoption  in  the  N.  F, 
