Am  Jour  Pharm.)        ^  Delicatc  Tcst  fov  AcetmiUid.  260 
June,  1911.      j  ' 
mark,  again  siphon  off  the  supernatant  liquid  and  add  2500  Cc.  of 
distilled  water,  stir  well  and  set  aside  to  settle  to  the  1000  Cc.  mark, 
siphon  off  the  supernatant  liquid  and  dilute  the  magma  with  dis- 
tilled water  until  it  measures  4000  Co.,  stir  well  and  set  aside  to 
settle  to  the  1000  Cc.  mark,  draw  off  the  clear  liquid,  mix  the  magma 
well  and  assay  by  the  process  given,  and  dilute  if  necessary  so 
that  the  preparation  will  contain  7.5  per  cent.  Mg  (OH)o. 
ASSAY  PROCESS. 
To  10  Cc.  accurately  measured  in  a  cylinder  and  washed,  with 
several  portions  of  distilled  water,  into  a  titrating  flask  add  two 
drops  of  Phenolphthalein  T.  S.  and  30  Cc.  of  Normal  Sulphuric 
Acid  V.S.  the  solution  is  then  heated  to  insure  complete  reaction, 
and  titrated  back  with  Normal  Potassium  Hydroxide  V.S.  to  the 
neutral  point,  the  amount  of  Normal  Potassium  Hydroxide  V.S. 
used  deducted  from  the  amount  of  acid  previously  added  gives 
the  amount  Normal  Sulphuric  Acid  required  to  neutralize  the 
Magnesium  Hydroxide  present,  which  should  be  at  least  26.  Cc. 
Normal  Sulphuric  Acid  V.S.  corresponding  to  7.5322  per  cent,  of 
Magnesium  Hydroxide  held  in  suspension. 
With  this  formula  and  the  process  of  assay  it  will  be  an  easy 
matter  to  always  make  a  product  of  definite  strength  and  one  that 
is  always  uniform. 
A  DELICATE  TEST  FOR  ACETANILID. 
By  G.  N.  Watson, 
Assistant  in  Drug  Laboratory,  University  of  Kansas. 
Acetanilid  when  heated  together  with  Boric  Acid  over  naked 
flame  until  the  Boric' Acid  melts  produces  a  yellow  residue  having 
a  peculiar  fragrant  odor  suggestive  of  Sweet  Clover  or  Arbutus. 
The  yellow  color,  however,  is  produced  by  either  Acetanilid  or 
Phenacetine.  Antipyrine  produces  a  pink  color  and  a  Naphthalene- 
like odor.  Phenacetine  produces  an  odor  but  characteristic  of  itself, 
more  faint  than  that  produced  by  Acetanilid  or  Antipyrine.  With 
mixtures  of  the  Three  Antipyretics,  the  fragrant  odor  produced  by 
the  action  of  the  Acetanilid  is  sufficient  to  produce  the  characteristic 
