486  Cat  Method  for  Testing  Digitalis,  i^^^^'.  {'^"';,fXIr  ^''Ti''''' 
One-Houk  Frog  Heart  Method.    Variety  Ran  a  Pii'Iens.    Temp.  20°  C. 
F.  E.  Digitalis. 
No.  416233. 
'  frog  in  Grammes 
Dose  per  Gramme 
Result 
40.9 
.000,50 
l>calinf>' 
42.9 
.000,60 
39-1 
.000,60 
34.0 
.000,70 
46.5 
.000,70 
42.2 
.000,75 
(( 
50.8 
.000,80 
38.8 
.000,80 
(( 
31.2 
.000,90 
(( 
38.2 
.000,90 
Stopped 
314 
.001,00 
n 
35-5 
^  .001,00 
(( 
F.  E.  Digitalis. 
No.  335929- 
28.9 
.000,90 
22.0 
.000,80 
i( 
21.0 
.000,70 
Ci 
27.6 
.000,70 
23.0 
.000,70 
30.5 
.000,70 
li 
42.9 
.000,70 
19-3 
.000,65 
Beating 
20.2 
.000,60 
Stopped 
23-5 
.000,60 
36.5 
.000,60 
a 
37-4 
.000,60 
Beating 
36.S 
.000,50 
The  assays  of  these  preparations  by  other  methods  have  been 
inserted  here,  with  the  behef  that  they  will  be  of  some  interest  to 
the  reader  if  closely  analyzed,  although  no  decided  conclusions  can 
be  drawn  from,  so  small  a  number.  Considering  F.  E.  Digitalis 
No.  416233  and  No.  335929  by  the  guinea  pig  and  frog  heart 
methods,  it  will  be  seen  that  while  they  show  almost  the  same 
result  on  the  guinea  pig,  there  js  a  decided  difference  on  the  frog's 
heart.  A  lack  of  relationship  in  the  results  obtained  by  these  two 
methods  has  been  observed  by  others.  Remembering  that  these 
fluids  test  the  same  on  the  guinea  pig,  consider  the  assays  by  the 
