PHARMACEUTICAL  NOTES. 
101 
subject  who  have  time  to  investigate  it  practically  and  particu- 
larly, to  ascertain  whether  the  addition  of  a  minute  proportion  of 
hyposulphite  of  soda  to  freshly  made  syrup  would  not  secure  it 
against  change. 
Brooklyn,  Feb.  1,  1868. 
PHARMACEUTICAL  NOTES. 
By  C.  Lewis  Diehl. 
CHLORATES  OP  THE  CINCHONA  ALKALOIDS. 
The  quinia  salt  has  lately  been  quite  frequently  called  for  in 
this  city,  and  for  some  time  I  had  considerable  difficulty  in  pre- 
paring a  handsome  article.  As  I  was  unable  to  obtain  chlorate 
of  baryta  in  this  city,  I  tried  various  methods  to  avoid  its  use,  but 
finally  was  compelled  to  prepare  some  of  the  baryta  salt,  and 
then  following  the  process  of  Tichborne,  as  near  as  I  recollected, 
for  preparing  chlorate  of  quinia,  obtained  a  very  handsome  pro- 
duct. For  .the  convenience  of  those  that  are  unable  to  procure, 
or  wish  to  prepare  chlorate  of  baryta,  I  have  appended  below  the 
formula  for  preparing  this  salt,  which  is  essentially  that  of  Bott- 
ger,  as  given  in  Graham  Otto's  Lehrbuch  der  Chemie. 
Chlorate  of  Quinia.  Heat  1  gallon  of  distilled  water,  to  which 
a  small  quantity  of  solution  of  chlorate  of  baryta  has  been 
added,  to  near  the  boiling  point,  and  gradually  add  5  oz.  of  pure 
sulphate  of  quinia.  Then  add  solution  of  chlorate  of  baryta  in 
fractional  quantities,  until  a  portion  of  the  liquid,  when  filtered 
from  sulphate  of  baryta,  is  no  longer  precipitated  by  the  baryta 
salt,  and  forms  a  decided  precipitate  on  the  addition  of  dilute 
sulphuric  acid.  Now  filter  the  solution  and  allow  it  to  stand  for 
24  hours,  when  the  chlorate  will  have  crystallized  in  handsome 
acicular  needles,  which  are  arranged  in  mushroom-shaped  tufts. 
Drain  the  crystals  in  a  funnel,  and  dry  in  the  air  on  filtering 
paper,  placed  on  a  porous  tile. 
By  following  these  directions  the  operator  cannot  fail  to  obtain 
a  handsome  product.  The  first  portions  of  the  filtrate,  as  they 
drop  into  a  cold  vessel,  will  appear  milky ;  but,  as  the  filtrate 
accumulates,  the  precipitate  is  redissolved,  and  the  solution  re- 
mains clear  until  all  is  filtered.    This  circumstance  will  serve  as 
