102 
PHARMACEUTICAL  NOTES. 
a  guide  to  the  proper  concentration  of  the  solution ;  for  if  the 
solution  is  more  concentrated,  the  crystals  formed  will  be  very 
small ;  if  less  concentrated,  it  will  crystallize  in  needles  an  inch 
or  more  in  length  frequently,  which  when  dry  possess  a  pearly 
lustre,  and  in  individual  tufts  are  very  handsome,  but  present  a 
very  poor  appearance  in  bulk.  The  mother  liquors  will  yield 
another  crop  of  crystals,  but  are  best  reserved  for  a  future  ope- 
ration. A  small  amount  of  chlorate  of  baryta  is  recommended 
to  be  added  to  the  hot  water  before  the  addition  of  the  sulphate 
of  quinia,  as  by  that  means  the  latter  appears  to  dissolve  more 
rapidly. 
The  dried  salt,  as  thus  prepared,  is  perfectly  white,  and  pre- 
sents a  very  handsome  appearance.  It  is  but  sparingly  soluble 
in  cold  water,  but  freely  soluble  at  a  boiling  temperature.  It  is 
very  freely  soluble  in  alcohol  and  chloroform,  and  freely  soluble 
in  ether.  Placed  on  heated  platinum  foil,  it  forms  small  oily 
globules,  and  immediately  thereafter  deflagrates,  leaving  no 
residue. 
Bichlorate  of  Quinia.  During  my  experiments  on  the  chlo- 
rate of  quinia  I  decomposed  some  bisulphate  of  quinia  with  chlo- 
rate of  baryta,  adding  the  latter  to  exact  saturation.  The  filtered 
solution  was  evaporated  to  a  syrupy  consistence,  and  allowed  to 
stand  in  a  cool  place  for  a  number  of  days,  to  permit  the  forma- 
tion of  crystals.  No  crystals  having  formed,  it  was  evaporated 
carefully  to  dryness,  by  which  it  'unfortunately  became  somewhat 
colored. 
This  product  has  a  brownish  tinge,  is  freely  soluble  in  cold  and 
boiling  water,  moderately  freely  soluble  in  alcohol,  but  appa- 
rently insoluble  in  ether  or  chloroform.  When  placed  on  heated 
platinum  foil  it  immediately  explodes  with  great  violence,  leaving 
no  residue.  I  have  made  no  further  experiment  with  this  com- 
pound, but  consider  it  probable  that  by  proper  manipulation  a 
crystalline  compound  may  be  obtained.* 
Chlorate  of  Cinchonia.    This  salt  may  be  prepared  from  sul- 
[  *  Perchlorates  of  the  Cinchona  alkaloids  are  described  in  the  17th 
volume  of  Gmelin's  Handbook,  made  by  precipitating  their  sulphates  by 
perchlorate  of  baryta.  They  are  all]  crystalline. — Editor  Amer.  Journ 
Pharm.] 
