210 
CHLORODYNE. 
manipulation  of  pharmaceutical  agents  it  is  not  imitation  so  much 
that  should  be  arrived  at,  as  the  correct  therapeutical  effects. 
The  mode  by  which  I  have  made  it  during  the  past  year  is  as  . 
follows : 
Take  of  Sulphate  of  Morphia,  grs.  Ixiv. 
Alcohol,  95  per  cent.,  fgij. 
Chloroform  Purif.  f^vj- 
Sulphuric  Acid,  q.  s. 
Ext.  Cannabis  Ind.  (Allen's)  ^ss. 
Oleoresin  of  Capsicum,  gtts.  xij. 
Hydrocyanic  Acid,  (Scheele's)  gtts.  xcvj. 
Shake  together  the  sulphate  of  morphia,  alcohol  and  chloro- 
form, then  add  the  sulphuric  acid,  shake  well  until  it  becomes 
clear,  then  add  the  oleoresin  of  capsicum,  ext.  cannabis  and 
*  hydrocyanic  acid. 
This,  when  finished,  is  a  clear,  dark  green  liquid,  possessing  the 
acrid  taste  of  capsicum  and  odor  of  chloroform.  When  held  to 
sunlight  or  artificial  light,  it  has  a  dark  rich  claret  color.  It 
may  be  exhibited  in  doses  from  fifteen  to  thirty  drops.  It  has 
been  extensively  used  by  many  of  our  most  eminent  city  prac- 
titioners, who  prefer  it  to  Brown's  in  many  cases. 
I  have  often  heard  it  stated  that  one  of  the  principal  objec- 
tions against  the  use  of  chlorodyne,  is  to  the  fact  of  it  contain- 
ing ext.  cannabis,  which,  however,  appears  to  be  modified  in  this 
article  by  the  other  constituents. 
So  much  was  our  preparation  admired  that,  in  the  space  of  a 
year,  we  had  dispensed  over  one  hundred  ounces  entirely  upon 
prescriptions.  There  is  a  preparation  made  by  a  leading  firm  in 
Philadelphia  to  which  mine  corresponds  in  appearance,  but  the 
objection  to  it  is,  it  deposits  a  small  quantity  of  morphia  upon 
standing  a  little  time. 
I  also  examined  another  preparation,  made  by  an  assistant  of 
Davenport,  the  proprietor  of  Brown's  Chlorodyne,  which  it 
strongly  represents.  One  serious  objection  against  this  was  that 
it  was  designed  to  be  given  in  teaspoonful  doses.  Chlorodyne  has 
become  so  popular  among  physicians  that,  if  they  should  prescribe 
it,  not  knowing  it  was  made  of  this  strength,  they  might  be  dis- 
appointed in  its  effect.     Hence  the  necessity  of  having  a  prepa- 
