NITROGLUCOSE. 
345 
acid,  previously  mixed  with  water.  Rub  the  hypophosphite  to 
fine  powder,  and  pour  on  it  the  solution  of  the  sulphate  of  iron. 
Triturate  together  for  two  or  three  minutes,  then  pour  the  mix- 
ture on  to  a  piece  of  damped  calico,  and  squeeze  out  the  liquid 
as  far  as  possible  with  the  hands.  Filter  the  solution  so  ob- 
tained into  a  measure-glass,  and  add  to  it  seven  times  its  volume 
of  strong  syrup.  The  resulting  syrup  contains  2  grs.  of  hypo- 
phosphite  of  iron,  Fe(PH202)2  m  eacn  fluid-drachm.  The  time 
occupied  in  its  preparation  need  not  exceed  a  quarter  of  an 
hour.  As  hypophosphite  of  lime  is  now  in  general  use,  the 
materials  are  always  at  hand,  and  the  syrup  may  therefore  be 
prepared  at  the  time  it  is  wanted,  its  goodness  and  uniformity 
being  thereby  ensured.  It  is  true  that  the  syrup  so  obtained  is 
contaminated  with  minute  quantities  of  lime  and  sulphuric  acid. 
But  it  must  be  borne  in  mind  that  the  amount  of  sulphate  of 
lime  held  in  solution  by  oz.  of  liquid  is  so  small  that  its  pro- 
portion in  the  syrup  must  be  very  minute. 
It  is  very  probable  that  this  process  for  preparing  the  syrup 
has  been  resorted  to  by  other  operators,  but  as  no  description  of 
it  has  been  published,  it  seemed  desirable  to  give  it  insertion  in 
the  Pharmaceutical  Journal.  It  is  obvious  that  the  same  method 
is  applicable  to  the  production  of  the  syrup  of  hypophosphite  of 
iron  and  quinine, — sulphate  of  quinine  being  decomposed  by 
hypophosphite  of  lime  in  the  presence  of  a  free  acid. — Lond. 
Pliar m.  Jour?i.,  April,  1868. 
NITROGLUCOSE. 
By  M.  Carey  JL«ea. 
As  nitroglucose  has  been  much  less  studied  than  its  congen- 
eric nitro-substitution  compounds  pyroxyline,  xylodine  and  nitro- 
glycerine, a  few  words  on  its  preparation  and  properties  may 
not  be  uninteresting. 
The  substitution  does  not  take  place  in  sugar  with  quite  the 
same  facility  as  cellulose ;  the  acids  need  to  be  stronger  and  the 
temperature  lower.  The  sugar,  moreover,  appears  at  first  to 
dissolve,  and  then  to  separate  out  again,  in  the  form  of  a  greyish 
paste,  which  when  thrown  into  water  and  freed  from  the  adher- 
ing acid,  becomes  nearly  white. 
