536       ON  THE  PHYSIOLOGICAL   ACTION  OF  PAPAVERINA. 
materials  are  sucked  up  first,  and  made  sure  of,  while  by  the 
old  method  they  are  apt  to  be  left  behind  in  the  cup  or  spoon. 
6.  The  act  of  sucking  being  instinctive,  there  is  no  choking  nor 
sputtering,  consequently  no  loss  of  medicine,  nor  uncertainty  as 
to  how  much  has  been  taken,  and  no  soiling  of  the  infant's  or 
nurse's  clothes. 
7.  A  dose  may  be  given  to  the  infant  while  asleep,  without  its 
being  roused,  the  application  of  the  teat  to  its  lips  being  generally 
sufficient  to  make  it  suck  in  its  sleep. 
It  has  been  thought  that  adults  should  not  be  entirely  excluded 
the  benefits  of  anything  which  facilitates  or  felicitates  the  deglu- 
tition of  drugs,  for  it  is  astonishing  how  many  a  man  will  behave 
himself  like  a  baby  when  he  has  a  dose  of  Gregory  under  his 
nose ;  nor  yet  is  it  to  the  weak-willed  specimens  of  their  species 
only  that  the  adult's  siphon  medicine  glass  will  commend  itself. 
It  is  simply  an  acid  tube  fitted  to  a  graduated  glass  of  a  deeper 
pattern  than  usual,  and  may  be  used  with  convenience  and  ad- 
vantage wherever  an  acid  tube  is  required. — London  Pharm. 
Journ.,  Sept.,  1868. 
ON  THE  PHYSIOLOGICAL  ACTION  OF  PAPAYERINA. 
Dr.  Hofman,  after  taking  two  grains  of  the  muriate  of  papa- 
verin,  remained  awake  fifteen  hours,  fell  asleep  at  one  A.  M.,  and 
slept  only  five  hours.  From  four  grains  remained  awake  four- 
teen hours,  and  then  slept  six  and  a  half  hours.  From  six 
grains  experienced  violent  hiccough,  which  ceased  in  ten  minutes  ; 
tongue  became  moderately  coated,  and  had  discomfort  in  stomach  ; 
half  hour  after  dinner  wTas  attacked  with  severe  pain  in  the 
forehead,  without  confusion  of  ideas,  or  debility,  all  of  which 
passed  off  after  a  short  walk;  in  fourteen  hours  he  fell  asleep 
and  slept  six  hours.  Felt  perfectly  well  on  the  following  and 
succeeding  days.  He  then  took  six  grains  more,  with  only 
slight  disturbance  of  the  stomach.  His  pulse  fell  from  eighty- 
eight  to  sixty-four,  respiration  from  thirteen  to  eleven;  his  tem- 
perature remained  about  thirty-five  or  thirty-six  degrees  centi- 
grade. He  concluded  that  papaverin  does  not  cause  the  slightest 
inclination  to  sleep,  or  relaxation  of  the  muscles,  and  hence  is 
