98 
Belladonna  and  Hyoscyarnus. 
J  Am.  Jour.  Pharm. 
\      March,  1915. 
B.  This  grade  breaks  with  a  short  fracture,  showing  a  rather  soft, 
more  or  less  mealy  surface  of  a  brick-red  or  orange  color,  the  resin 
cells  not  being  perceptible  to  the  naked  eye. 
C.  This  grade  breaks  with  a  short,  waxy  fracture,  and  shows  a 
liver-brown  or  reddish-brown  color. 
The  rhizomes  collected  for  experimental  work  were  of  typical 
Sanguinaria  canadensis  Lin.,  and  corresponded  to  grade  A  as  above 
outlined;  the  commercial  drug  assayed  for  comparison  showed  a 
higher  percentage  of  alkaloid  than  that  specially  collected. 
The  assays  were  made  by  Mr.  J.  B.  Williams,  of  the  Scientific 
Laboratory. 
Assay  of  Commercial  Drug,  Sanguinaria. 
P    j  Moisture,  Sanguinarine, 
r  per  cent.  per  cent. 
A  6.68  6.95 
B  6.8o  6.oi 
C  6.6  7.01 
Assay  of  Collected  Samples  of  Air-dried  Sanguinaria. 
Time  of  Moisture,  Sanguinarine 
collection  per  cent.  per  cent. 
II/13/13  79.84  4.75 
1/16/14   78.71  4.7O 
3/18/14  :  84.24  4.84 
4/16/14  (Flowering  season)   85.54  6-53 
5/28/14  (Fruiting  season)   79-20  5.10 
6/19/14  (After  fruiting  season)   76.50  5.00 
7/30/14  (Just  after  death  of  foliage)   76.12  5.00 
10/29/14  Artificialh-  dried   79-88  4.93 
Assay  of  Collected  Samples  of  Air-dried  Rootlets  of  Sanguinaria 
Time  of  collection 
per  cent.         per  cen 
November,  1913,  to  July,  1 914  •  79.5  1.77 
BELLADONNA  AND  HYOSCYAMUS. 
By  Oliver  A.  Farwell,  Department  of  Botany,  Parke,  Davis  &  Co., 
Detroit,  Mich. 
Much  has  been  written  of  late  about  the  cultivation  of  belladonna 
and  hyoscyarnus  for  commercial  purposes.  It  has  been  shown  that 
belladonna  is  hardy  as  far  north  as  Xew  York.  Henbane  is  a 
much  hardier  plant  and  is  known  to  be  well  established  on  Mackinac 
Island,  in  the  Straits  of  Mackinac,  between  the  two  peninsulas 
