4io 
Inversion  of  Cane  Sugar  in  Syrups.  j 
Vinum  Carnis  et  Ferri. 
Wine  of  Beef  and  Iron. 
Extract  of  beef  
Water,  hot  
Iron  and  ammonium  citrate  , 
Syrup  
Alcohol    
Compound  spirit  of  orange  
Ammonia  water,  a  sufficient  quantity, 
Sherry  wine,  a  sufficient  quantity, 
Beef,  Wine  and  Iron. 
30  Gm. 
60  Cc. 
10  Gm. 
100  Cc. 
50  Cc. 
1  Cc. 
To  make 
1000  Cc. 
Dissolve  the  extract  of  beef  in  the  hot  water,  add  the  syrup  and 
then  the  compound  spirit  of  orange  and  alcohol  previously  mixed. 
Dissolve  the  iron  and  ammonium  citrate  in  750  Cc.  of  sherry  wine, 
and  add  this  solution  to  the  other  mixture,  then  add  sufficient  am- 
monia water  to  make  the  solution  neutral  or  only  very  faintly  alkaline 
to  litmus  paper,  then  add  sufficient  sherry  wine  to  make  1000  Cc. 
If  acid,  now  add,  drop  by  drop,  ammonia  water  untihneutral  or  very 
faint  alkaline  reaction  is  obtained.    Set  aside  for  two  days  and  then 
On  June  25,  1912,  a  type  sample  of  wine  of  beef  and  iron  for  the 
N.  F.  Revision  was  made  by  the  above  formula.  An  eight-ounce 
bottle  of  this  has  been  kept  under  observation  since  that  date.  For 
a  time  it  was  kept  in  the  cellar,  and  has  more  recently  been  in  the 
laboratory,  subjected  to  the  varying  changes  of  temperature  and 
more  or  less  exposed  to  the  light.  At  this  date,  nearly  three  years 
after  preparation,  it  is  still  clear,  free  from  precipitation,  and  is 
entirely  satisfactory. 
In  the  February,  1902,  issue  of  the  Druggists'  Circular  (page  27), 
in  an  article,  "  Fallacious  Tests  for  Glucose  in  Cane  Sugar  Syrup,"  I 
showed  that  syrupus  made  according  to  the  official  formula  by  the 
hot  process  did  not  contain  more  than  a  very  faint  trace  of  reducing 
filter. 
INVERSION  OF  CANE  SUGAR  IN  SYRUPUS.1 
By  Joseph  L.  Mayer. 
1  Read  before  the  New  York  State  Pharmaceutical  Association,  June  29, 
I9I5- 
