Am.  Jour.  Pharm.  ) 
Jan  1,  1873.  j 
New  Quinimetric  Process. 
27 
slightly  soluble  in  cold  water,  insoluble  in  alcohol  and  ether.  Ob- 
tained easily  by  double  decomposition  between  fresh  vanillate  of 
baryta  and  sulphate  of  magnesia,  or  by  saturating  a  boiling  solution 
of  vanillic  acid  with  magnesia  hydrate  or  carbonate,  and  allowing  to 
cool  slowly. 
Vanillate  of  Zinc  (C16H7Zn06). — Deposited  in  white  crystals  upon 
cooling  a  hot  solution  of  vanillic  acid,  saturated  by  oxide  or  carbonate 
of  zinc.    Slightly  soluble  in  boiling  water. 
Iodine  Compounds  (C16H7IOG  and  C16H6T20G). — The  first  consisting 
of  white  pearly  crystals  of  faint  odor,  slightly  soluble  in  alcohol  and 
ether,  melting  at  74°  and  subliming  without  decomposition,  was 
deposited  after  some  hours  from  a  mixture  of  2  grams  of  vanillic  acid 
dissolved  in  50  grams  of  water  and  1*5  gram  of  iodine  dissolved  in  50 
grams  of  alcohol.  The  second  was  obtained  when  iodine  was  used  in 
excess,  also  as  pearly  crystals.  It  is  slightly  soluble  in  boiling  water, 
insoluble  in  cold  chloroform,  soluble  in  hot  ether  and  alcohol. 
Bromine  Compound  (C16H6B206). — Pearly,  yellowish,  odorless  crys- 
tals, very  slightly  soluble  in  water,  more  so  in  alcohol,  ether  and  chlo- 
roform, obtained  by  gradually  adding  slight  excess  of  bromine  to  a. 
concentrated  aqueous  solution  of  vanillic  acid,  and  crystallizing  the 
precipitate  first  from  alcohol  and  then  from  boiling  water. 
Vanillic  acid  being  ignited  with  potash,  and  the  mass  afterwards 
treated  with  water,  hydrochloric  acid  and  ether  yielded  small  white 
inodorous  prismatic  crystals,  which  product  the  author  considers  to  be- 
a  new  acid  and  proposes  to  call  oxyvanillic  acid,  with  the  formula 
C18H808.  When  vanillic  acid  was  heated  in  a  sealed  tube  with  hydri- 
odic  acid,  the  methyl-hydriodic  was  obtained. 
From  these  experiments  M.  Carles  is  led  to  conclude  that  the  efflo- 
rescence on  vanilla  is  neither  of  the  substances  that  have  heretofore 
been  described,  but  is  a  peculiar  acid,  isomeric  with  anisic,  formoben- 
zoic,  methylsalicyclic,  creasotic,  oxytoluic,  and  many  other  acids. — - 
Pharm.  Journ.,  Lond.,  Nov.  23,  1872. 
DESCRIPTION  OF  A  NEW  QUINIMETRIC  PROCESS. 
By  P.  Carles. 
Having  ascertained,  by  experiment,  that  the  quinimetric  methods  in 
use  are  not  suited  for  extracting,  in  a  sufficiently  pure  state  to  admit  of 
