^iii7i;m3RM'}    Exiractum  Ipecacuanhas  Flu  id  urn.  213 
The  dried  residue,  after  powdering,  was  wet  up  with  water  (weight 
of  16  f.  oz.  water  about  7,300  grains)  and  exhausted. 
1  Pint  weighed  7,630  grains.    Difference,  330  grains.    Extract,  734  grains. 
2  "         "       7,415     "  "  115     "  "       255  " 
3  "        "       7,335     "  "  35      "  "        77  « 
480  grains.  1,066  grains. 
Quantity  residue  percolated  .  .  .  6,320  grains. 
Dried  residue,  after  exhaustion    ....      5,252  " 
Loss  by  percolation,  solid  extract        .  .  .      1,068  grains. 
The  three  pints  aqueous  percolate  when  evaporated  to  dryness, 
gave  of  extract  1,150  grains.  This  extract  has  a  perceptible  odor, 
and  in  10  grain  doses  produced  nausea  and  slight  emetic  effect ;  its 
taste  is  peculiar  and  disagreeable.  Ten  grains  of  the  extract  would 
be  equivalent  to  seventy  grains  of  the  powder,  if  the  former  had 
special  medicinal  value.  The  separation  of  resin  from  fluid 
ipecac  is  difficult ;  the  Pharmacopoeia  process  of  I860  will  not  effect 
its  removal.  The  formula  directs  10  f.  oz.  water  with  1  f.  oz.  acetic 
acid  to  be  mixed  with  the  concentrated  alcoholic  extract — the  writer 
has  found  it  necessary  to  use  from  five  to  ten  pints  of  water  with  1  f. 
oz.  acetic  acid  for  every  Pharmacopoeia  portion — frequently  this  dilu- 
tion is  repeated  before  the  preparation  is  free  from  resin. 
One  pint  of  fluid  ipecac,  made  by  the  old  process,  weighs  about 
7,980  grains  at  65°F.  Fluid  extract  of  ipecac  prepared  by  the  pro- 
cess given  in  the  1860  Pharmacopoeia,  is  rarely  found  free  from  resin ; 
the  following  formula  for  syrup  of  ipecac  has  proved  reliable,  pro- 
ducing a  clear  elegant  syrup  : 
Fluid  Ipecac        f.  oz.  j. 
Water  f.  oz.  xvij. 
Gran.  Sugar,       Troy  oz.  xij. 
Dilute  the  fluid  extract  with  16  f.  oz.  water,  set  aside  for  12  hours, 
filter,  evaporate  to  6  f.  oz.,  filter,  add  through  filter  1  f.  oz.  water, 
then  dissolve  sugar  with  gentle  heat,  the  finished  syrup  to  measure 
16  f.  oz. 
The  conclusion  of  these  experiments  indicate  that  the  old  formula 
is  reliable  and  economical,  though  difficult  in  manipulation.  The 
physician  rarely  has  cause  to  criticise  the  effectiveness  of  fluid  ipecac 
when  prepared  from  good  root,  and  by  the  old  process. 
