540 
Solution  of  Iodoform. 
J  Am.  Jour.  Phabm. 
\     Dec.  1, 1873. 
dilute  sulphuric  acid,  and  nine  fluid-drachms  of  infusion  of  roses,  the 
precipitate  of  tannate  of  quinia  which  forms  is  dissolved,  and  the  re~ 
suit  is  a  beautiful  bright  solution.  The  precipitate  which  occurs  in 
gargles  containing  tannic  acid  and  infusion  of  roses  can  also  be  dis- 
solved by  the  addition  of  two  fluidounces  of  glycerin  to  the  pint. — 
Pharm.  Journ.  (Lond.\  Nov.  8,  1873. 
NOTE  ON  A  SOLUTION  OF  IODOFORM. 
By  Louis  Elsberg,  M.  D., 
Professor  of  Laryngology  and  Diseases  of  the  Throat  in  the  University  of 
New  York. 
A  great  objection  to  the  employment  of  iodoform  (C2HI3)  in  sub- 
stance is  its  bad  odor,  which  is  very  penetrating  and  persistent ;  fur- 
thermore, there  has  not  hitherto  been  in  use  any  effective  solution  for 
topical  application  in  cases  where  ointments  are  inapplicable.  It  will 
doubtless  be  of  interest  to  all  who  know  the  medicinal  value  of  iodo- 
form to  learn  that  both  these  objections  have  been  overcome.  I  have 
found  an  ethereal  solution  which  deodorizes  iodoform,  the  solution 
smelling  of  ether  only,  and  at  the  same  time  constitutes  an  effective 
topical  remedy  for  diseased  mucous  membranes,  as  of  the  throat,  nose, 
mouth,  larynx,  vagina,  rectum,  etc.  Rhighini  used  an  ethereal  solu- 
tion for  direct  inhalation,  and  Dr.  Sass  used  an  ethereal  solution  and 
also  a  mixture  of  iodoform  and  sweet-almond  oil-by  means  of  a  spray- 
producer  for  inhalation.  Dr.  Gubler  requested  Messrs.  Odin  and 
Leymarie  to  ascertain  the  relative  proportions  in  which  iodoform  is  so- 
luble in  ether,  and  the  most  favorable  conditions  for  its  preparation  ; 
their  experiments  and  conclusions  are  published  in  the  Pharmaceuti- 
cal Journal,  August  2,  1873.  The  London  Doctor  for  September  1 
tells  us  that  experiments  were  made  with  pure  ether  of  65°  Baumd 
(specific  gravity  .724),  and  also  with  ether  of  62°  Baumd  and  56° 
Baume,  the  temperature  being  13°  C.  Eight  grains  of  tincture  ob- 
tained with  these  ethers  pontained  iodoform  in  solution,  respectively, 
to  the  following  extent : 
Ether  of  65°  Baume,  1.61  grammes. 
"        62°     "       1.26  " 
56u     "      1.13  " 
The  conclusions  drawn  by  the  authors  from  their  experiments  are : 
1.  To  employ  iodoform  in  the  crystalline  state. 
