Am.  Jour.  Pharm. 
May,  1898. 
}    Recent  Literature  Relating  to  Pharmacy. 
245 
to  5  per  cent,  solution  of  potassium  permanganate,  as  this  salt  in 
the  proportion  of  one  to  twenty  destroys  this  poison. —  The  Prac- 
titioner, February,  1898. 
The  Gazette  hebdomadaire  de  medicine  et  de  chirurgie,  February 
10th,  attributes  the  following  formula  to  Desnoyer : 
M. — The  cavity  is  washed  and  dried,  and  a  little  pellet  of  cotton  soaked  in 
the  solution  is  inserted.  Over  this  another  pellet  of  cotton  charged  with 
tincture  benzoin  is  placed.  The  lemon  is  used  simply  to  mask  the  odor  of  the 
carbolic  acid. 
RECENT  LITERATURE  RELATING  TO  PHARMACY. 
Peter  Boa  [Pharmaceutical  Journal,  February  26,  1898)  in  com- 
menting upon  the  method  of  the  British  Pharmacopoeia  for  the  above 
preparation  says  that  it  is  a  process  of  double  maceration  with  cold 
water,  heating  to  boiling  point,  straining,  evaporation  to  a  specified 
gravity  when  cold,  and  preservation  by  spirit.  Continuing,  he  says 
that  two  points  deserve  notice  as  being  characteristic  of  this  fluid 
extract.  One  is  that  it  has  to  be  evaporated  so  that,  when  cold,  it 
shall  have  a  specified  gravity  of  ri6o ;  the  other  is  that  only  one 
sixth  of  its  volume  of  spirit  has  to  be  added,  presumably  to  pre- 
serve it.  In  short,  the  object  is  to  extract  the  sweet  principle  with 
water,  which  at  the  same  time  takes  out  albuminous  and  mucilagin- 
ous matter ;  to  coagulate  the  albumen  by  heat  and  remove  it  by 
straining,  and  finally,  for  preservative  purposes,  to  add  the  spirit 
which  still  further  clears  the  extract  by  throwing  down  part  of  the 
mucilaginous  matter. 
In  comparing  the  product  made  according  to  the  above  process 
with  that  made  according  to  the  U.S. P.  method,  he  found  the  latter 
to  compare  very  unfavorably  with  the  former.  It  had  an  acid  bitter 
flavor  which  quite  overpowered  the  sweetness ;  while  the  B.P. 
extract  possessed  a  sweet  mellow  taste,  free  from  acidity  and  with 
only  a  faint  bitterness.  The  bitterness  of  the  U.S. P.  extract  was 
accounted  for  by  the  fact  that  licorice  root  contains,  besides  the 
sweet  principle,  an  oleoresinous  acrid  principle  and  a  bitter  prin- 
AN  APPLICATION  FOR  DENTAL  CARIES. 
R  .    Crystallized  carbolic  acid, 
Essence  of  lemon, 
Alcohol, 
10 
FLUID  EXTRACT  OF  LICORICE. 
