Am.  Jour.  Pbarm.^ 
September,  1898.  J 
Aromatic  Waters. 
445 
From  this  oil  aromatic  water  was  prepared  by  the  calcium  phos- 
phate process  directed  for  official  waters  of  the  Pharmacopoeia  of 
1890,  by  the  cotton  process  of  1880,  the  percolation  being  con- 
ducted at  the  rate  of  30  drops  a  minute,  by  simple  agitation  of  the 
oil  with  water  at  ordinary  temperature  for  two  days  and  subsequent 
filtration,  and  lastly  by  hot  solution,  the  process  being  performed 
by  heating  the  oil  and  water  for  fifteen  minutes  in  a  flask  with  up- 
right condenser  attached,  the  solution  on  cooling  being  filtered. 
This  modification  of  the  usual  hot-water  process  is  an  improvement 
in  that  the  shaking  of  a  hot  flask  is  obviated  and  that  the  loss  of 
oil  by  evaporation  is  reduced  to  the  minimum.  In  all  the  methods 
employed,  the  pharmacopceial  ratio  of  oil  and  water  (2  to  1,000) 
was  followed. 
The  finished  waters  were  assayed  by  the  volumetric  process  of 
Simonson  and  Ewing  (Proc.  A.  Ph.  A.,  40,  p.  196),  modified  by 
Kremers  and  James  (Ph.  Rev.,  16,  p.  130),  namely,  saponification 
with  a  definite  quantity  of  normal  volumetric  solution  of  potassium 
hydrate  and  titration  of  the  excess  of  alkali  with  decinormal  acid. 
The  difference  in  quantity  of  alkali  before  and  after  saponification, 
represents  the  quantity  used  by  the  oil  of  wintergreen,  and  this, 
expressed  in  cubic  centimetres  of  normal  alkali,  multiplied  by  the 
methyl  salicylate  factor,  0-152,  gives  the  quantity  of  oil,  in  grammes, 
in  the  sample. 
The  result  of  these  assays  were  as  follows  : 
Ouantity 
Amount  Normal 
Alkali  used  in 
Amount  of  Oil 
of  Water 
Saponification 
in  Sample 
Percentage 
Process. 
used  (C.C.). 
(in  C.C.). 
(in  Grammes). 
of  Oil. 
Calcium  phosphate  a  .  .  . 
50 
0*23 
0-03496 
0*06992 
b  .  .  . 
50 
0"22 
0-03344 
0-06688 
40 
o'i6 
0-02432 
0-0608 
b   
40 
0*17 
0-02584 
0-0646 
Agitation  with  water  a  .  . 
40  , 
o*i6 
0-02432 
0-0608 
b  .  . 
-  40 
0-17 
0-02584 
0  -0646 
Hot  water  with  upright 
condensation  a  I  ... 
50 
0-28 
0-04256 
0*08512 
Hot  water  with  upright 
condensation  a  II  .  .  . 
50 
0*29 
0*04408 
0-08816 
Hot  water   with  upright 
condensation  b    .  .  .  . 
50 
0-23 
0-03496 
0-06992 
Samples  a  and  b  in  each  case 
are  from  different  lots,  and  it  will 
be  seen  that  each  pair  agree  fairly  well,  except  the  two  batches 
