98  Spurious  Cubebs. 
The  following  remarks  apply  to  the  residue  obtained 
( Am.  Jour.  Pharm. 
[       Feb.,  1886. 
Character  of  residue. 
Piper  Oubeba. 
Piper  crassipes. 
Daphnidium  Oubeba. 
Oleo-resinous,  dull 
yellow  color. 
Oleo-resinous,  olive- 
green  color. 
Fatty,  brown  color. 
The  filtered  solution 
obtained  after  boil- 
ing the  residue  with 
10  c.e.  of  water. 
Colorless,  free  from 
bitterness ;  sparing- 
ly reduced  Fehling's 
solution. 
Colorless,  very  bitter, 
like  quassia;  copi- 
ously reduced  Feh- 
ling's solution-. 
Colorless,  very  bitter ; 
sparingly  reduced 
Fehling's  solution. 
A  few  drops  of  the 
above  solution 
treated  with  H2SO4 
upon  a  white  tile. 
Developed  a  crimson 
color  (characteristic 
of  cube  bin). 
Developed  a  brown 
color. 
Xo  change. 
Portion  of  original 
residue  treated  on 
a  white  tile  with 
H2S04- 
With  H2SO4-I-HNO3. 
Crimson. 
Crimson,  changing  to 
violet. 
Brown. 
Green,  fading  to  yel- 
low. 
Brown. 
Brown. 
V.  The  marc  from  IV.  washed  and  dried  was  macerated  in  100  c.e. 
absolute  alcohol  for  five  days.  Five  c.e.  evaporated  to  dryness  in  a 
water-oven  yielded  a  residue  of  "015  gm.,  corresponding  to  3'0  per 
cent. 
VI.  The  marc  from  V.;  washed  and  dried,  was  macerated  in  100  c.e. 
of  distilled  water  for  five  days.  Ten  c.e.  evaporated  to  dryness  as 
above  yielded  a  residue  of  *16  gm.,  corresponding  to  16  per  cent. 
Ten  cc.  mixed  with  20  c.e.  absolute  alcohol,  set  aside  for  twenty- 
four  hours,  the  precipitate  collected,  washed  and  dried,  weighed  #1 
gm.,  corresponding  to  10  per  cent,  mucilaginous  matters. 
From  the  above  experiments  the  spurious  cubebs  under  investiga- 
tion are  free  from  tannin,  and  contain  essential  oil,  resin,  and  a  very 
bitter  glucoside,  but  to  which  of  the  two  latter  the  deleterious  effects 
already  recorded  may  be  attributed  remains  a  subject  for  physiological 
experiment.  In  conclusion,  the  authors  are  of  opinion  that  this  species 
agrees  entirely  with  that  described  by  Fliickiger  and  Hanbury,8  and 
may  be  definitely  referred  to  Piper  crassipes. — Phar.  Jour,  and 
Trans.,  Dec.  12,  1885. 
Compound  Fluid  Extract  of  15 u elm. — The  following  formula  which 
has  been  used  by  Dr.  H.  H.  Stin^on,  for  ten  years,  with  excellent  results,  is  recom- 
mended: Buchu  16  troy  ounces,  uva  ursi,  cubeb  and  juniper  berries,  of  each  4 
troy  ounces ;  prepare  in  the  usual  manner  28  fluid  ounces  of  fluid  extract,  using 
95  per  cent,  alcohol  for  the  menstruum. — N.  E.  Med.  Monthly,  December,  1885, 
p.  27.  
8  Pharmacographia,  p.  588. 
