104 
Varieties. 
(  Am.  Jour.  Pharm. 
[       Feb.,  1886. 
lishes  the  normal  type.  When  the  circulation  is  slower  the  medica- 
ment appears  to  immediately  obviate  the  functional  trouble,  maintaining 
and  augmenting  the  acquired  force  of  the  heart  muscle. — Bulletin 
General  de  Therapeutique,  December,  1885,  p.  528. 
VARIETIES. 
Fluid  Extract  of  Salix  Nigra,  prepared  from  the  inflorescence,  is  recom- 
mended by  Dr.  F.  T.  Paine,  in  drachm  doses,  for  neuralgia  and  dysmenorrhcea 
of  ovarian  origin,  in  the  treatment  of  masturbation. — Med.  Age. 
Bromhydrate  op  Quinine  and  Valerianate  op  Caffeine,  combined  in  the 
proportion  of  fifteen  grains  of  the  former  to  eight  grains  of  the  latter,  are  re- 
garded by  Dr.  Martinez  Cereceda  as  frequently  effectual  in  malarial  fevers? 
which  do  not  yield  to  the  sulphate  of  quinine  in  much  larger  doses.  The 
bromhydrate  of  quinine  has  a  gradual  sedative  action  upon  the  nervous  system, 
does  not  irritate  the  stomach,  and  its  use  is  followed  by  no  ill  effects. — Med. 
News,  1885 ;  Gaceta  de  los  Hosp. 
Hypnone,  a  new  hypnotic,  is  methylphenyl acetone.  It  is  the  principal  pro- 
duct, resulting  from  the  dry  distillation  of  calcium  benzoate  and  acetate,  and 
is  formed  also  by  the  action  of  zinc  methyl  upon  benzoyl  chloride.  It  crystal- 
lizes in  laminae,  and  melts  at  14°  C,  or,  according  to  others,  at  20.5°  C;  it  is  nearly 
insoluble  in  water,  slightly  soluble  in  glycerin,  readily  soluble  in  alcohol  and 
ether.  Dujardin-Beaumetz  states  that  it  should  be  used  only  in  cases  of  over- 
excitement  of  the  brain  and  not  where  there  is  pain.  The  dose  is  four  to  ten 
drops,  taken  at  once,  since  divided  doses  are  not  effectual.  Vigier  (Gaz.  held.) 
suggests  an  elixir,  prepared  in  the  following  proportion :  hypnone  1  drop,  alcohol 
(60  per  cent.),  and  syrup  of  peppermint,  of  each  3  grams. 
A  Mixture  of  Animal  Charcoal  and  Champhor,  equal  parts,  is  recom- 
mended by  Barbocci  as  an  application  to  prevent  the  offensive  odor  and  remove 
the  pain  of  old  excavated  ulcers. — British  Med.  Jour. 
Chloroform  as  a  Hemostatic  in  minor  surgical  operations,  especially  in  the 
mouth  and  throat,  is  recommended  by  Dr.  Spaak;  it  is  used  in  one  per  cent, 
aqueous  solution. —  Wien  Med.  Blatter,  1885,  No.  41. 
Alkaline  Toothwash. — Vigier  (Gaz.  hebd.)  recommends  the  following:  Dis- 
solve sodium  bicarbonate '20  grams  in  distilled  water  980,  and  add  sufficient 
distilled  spirit  of  peppermint.  Triturate  20  drops  of  the  best  oil  of  peppermint 
with  magnesium  carbonate  2  grams,  afterward  with  the  above  solution,  gradually 
added,  and  filter. 
Cauterizing  Crayons  are  recommended  by  Moser  (Z'  Union  Med.),  to  be  pre- 
pared from  charcoal  40,  potassium  nitrate  5,  porphyrized  iron  5,  powdered  ben- 
zoin 1,  and  sufficient  mucilage.  After  drying,  these  crayons  are  firm,  light 
easily  and  produce  immediate  cauterization. 
