114  Analysis  of  Aristolochia  Fcetida,  {AmMaren,iS&m* 
VI.  Hydrochloric  acid  (1  per  cent.)  dissolved  4*11  per  cent,  of 
organic  matter,  which  was  not  further  examined. 
The  residue,  after  drying,  amounted  to  52*68  per  cent.,  which  yielded 
3*75  per  cent,  to  chlorine  water,  thus  representing  48.93  per  cent,  of 
cellulose. 
75  grams  of  the  original  drug  were  distilled  with  milk  of  lime. 
The  first  portions  of  the  distillate  possessed  the  narcotic  odor  of  the 
drug  to  a  marked  degree.  On  shaking  this  with  chloroform  the  latter 
took  the  odor  and  the  alkaline  reaction  of  the  distillate.  The  chloro- 
form was  allowed  to  evaporate  spontaneously  and  the  residue  dissolved 
in  alcohol  gave  ammonia  on  heating  with  potassium  hydrate,  and  pre- 
cipitated with  a  number  of  the  alkaloidal  reagents. 
While  Ave  are  not  prepared  to  say  there  is  a  volatile  alkaloid  present, 
we  consider  the  evidence  in  favor  of  such  a  belief.  An  insufficient 
amount  of  material  and  the  approach  of  the  College  examinations  pre- 
vented further  work  on  this  interesting  material,  which  is  recom- 
mended in  the  Mexican  Pharmacopoeia  as  a  good  remedy  for  colic. 
From  other  sources  we  learn  it  has  been  used  for  tanning  purposes, 
but  judge  the  large  amount  of  coloring  matter  present  would  be  a 
serious  drawback. 
The  following  is  a  summary  of  the  constituents  found : — 
Moisture   14*10  per  cent. 
Ash   4*88  " 
Fixed  oil   1*95  «■ 
Resin   *50  " 
Soluble  in  absolute  alcohol :  tannin,  coloring  matter   7.64  " 
Soluble  in  water :  mucilage,  tannin  and  coloring  matter   10*24  u 
Alluminoids   1*90  " 
Soluble  in  dilute  hydrochloric  acid   4*11  " 
Lignin     52*68  " 
98*00 
Antipyrin  resembles  sodium  salicylate  in  its  action,  and  is  recommended  by 
Dr.  Neumann  (Berl.  Klin.  Woch.),  for  further  trial  in  chronic  rheumatism  of  the 
joints  and  in  rheumatic  neuralgia.  Dr.  A  Walker  {Brit.  Med.  Jour.,  Nov.  7, 1885) 
has  observed  it,  in  two  cases  of  typhoid  fever,  to  produce  reduction  of  tempera- 
ture to  about  normal,  and  good  refreshing  sleep  for  5  or  6  hours ;  15  grains  of 
the  remedy  were  given  at  9  P.  M.,  and  1\  grains  each  at  10  and  at  11  P.  M. 
Antipyrin  was  also  found  useful  to  produce  sleep  in  several  cases  of  pyrexia  in 
young  children.  Teaspoonful  doses  three  times  a  day  of  the  following  mixture 
have  been  used  by  Dr.  Dumolard  in  typhoid  fever :  Antipyrin  20,  Jamaica  rum 
30,  water  150,  and  syrup  150  grams. 
