Amjanue'"im^  Purdue  University.  293 
Bibliographical  Note  on  Nux  Vomica. — The  British  Pharma- 
copoeia having  recently  adopted  a  standard  based  upon  alkaloidal 
strength/ it  may  be  a  convenience  to  readers  to  refer  to  the  following 
articles  in  the  Pharm.  Jour,  and  Trans.,  relating  to  this  subject. 
References  are  made  to  volume,  page,  date,  author  and  topic.  The 
list  does  not  claim  to  be  complete. 
XIV  65 
July  28, 1883. 
Beckurts. 
Ferrocyanide  of  Strychnine. 
it 
290 
Oct.  13,  " 
Dunstan  & 
Short. 
Separation  of  Strychnine  as  Ferro- 
cyanide. 
tt 
292 
tt 
Tincture  of  Nux  Vomica. 
XI 
XI 
XI 
380 
400 
440 
Nov.  10,  " 
Nov.  17,  " 
Dec.  1,  " 
Hick. 
Tanner. 
Hick. 
1 
J 
Debate  on  Preparation  of  Tincture 
from  Fluid  Extract. 
XI 
441 
Dec.  8,  " 
Dunstan  & 
Short. 
Tincture  of  Nux  Vomica. 
xe 
443 
tt  it 
u 
Extract      "  " 
it 
450 
it  a 
Discussion  of  the  above  papers. 
xc 
461 
Dec.  15,  " 
Convoy. 
Tincture  of  Nux  Vomica. 
tt 
480 
Sandford. 
Tincture  from  Fluid  Extract. 
xt 
621 
Feb.  9,  1884. 
Dunstan  &• 
Short. 
Standard  Extract  of  Nux  Vomica. 
622 
a 
tt 
"       Tincture    "  " 
XI 
634 
Discussion  of  the  above  papers. 
XI 
851 
Apr.  19,  " 
Schacht. 
Extract  of  Nux  Vomica  and  Esti- 
mation of  Alkaloids. 
875 
Apr.  26,  " 
Dunstan. 
Eeply  to  Schacht. 
XI 
876 
Smith. 
tt 
896 
May  3,  " 
Schacht. 
"      "  Smith. 
tt 
1025. 
June  21,  " 
Dunstan  & 
Short. 
New  Glucoside  from  Nux  Vomica. 
XV  1 
July  5,  " 
tt 
a 
Chemistry  and  Botany  of  Ceylon 
Strychnos. 
it 
60 
July  19,  " 
Greenish. 
Seed  Hair  of  Strychnos. 
xt 
156 
Aug.  23,  " 
Dunstan  & 
Short. 
Summary  of  Papers. 
Physiological  Action  of  Adonidin.— Dr.  H.  A.  Hare  gives  the  fol- 
lowing conclusions  derived  from  an  experimental  study  of  adonidin: 
Adonidin  in  all  doses  increases  arterial  pressure  by  stimulating  the  vasomotor 
centres,  and  by  increasing  the  cardiac  force.  In  moderate  doses  it  increases,  the 
pulse-rate  and  force  from  the  first,  but  when  large  toxic  doses  are  given,  it  prim- 
arily slows  the  heart  by  stimulating  the  pneumoga^tric,  and  then  increases 
pulse-rate  by  depressing  the  inhibitory  nerves,  and  stimulating  the  accelerator 
apparatus.  The  slowing  of  pulse-rate  is  also  in  all  probability  due  in  part  to 
increased  arterial  pressure,  as  under  these  circumstances  the  blood-paths  are 
greatly  diminished  in  calibre.  On  the  nervous  system  the  drug  has  but  little 
action,  unless  the  quantity  administered  be  enormous.  Under  these  conditions 
it  paralyzes  the  sensory  side  of  the  cord,  but  has  no  effect  on  the  mofor  tract, 
or  on  the  efferent  or  afferent  nerve  trunks. —  Therapeutic  Gazette,  April  15,  1886. 
