Am.  J.  Ph.] 
8 
[July,  1886 
FILLED  SOLUBLE  ELASTIC  CAPSULES 
—OF— 
QUININE  SULPHATE 
—AND  OF— 
CINCHONIDIA  SULPHATE. 
We  take  pleasure  in  being  able  to  offer  the  profession  a  device  for  the  ex- 
hibition of  quinine  and  cinchonidia,  which  presents  many  points  of  superiority 
over  any  which  has  been  heretofore  suggested.  By  means  of  our  Soft  Elastic 
Capsules  the  objectionable  taste  of  the  drug  is,  of  course,  completely  concealed, 
while  the  ease  with  which  this  capsule  is  swallowed,  after  it  has  been  lubricated 
with  the  saliva,  makes  it  vastly  superior  to  a  pill  or  the  hard  capsule. 
We  manufacture  two  sizes  of  these  Quinine  and  Cinchonidia-Filled  Soft 
Elastic  Capsules,  containing,  respectively,  1,  2  and  3  grains,  and  4  and  5  grains 
of  the  salts.  While  each  of  these  two  sizes  contains  a  different  quantity,  the 
bulk  of  the  contents  does  not  vary  with  the  quantity  of  the  drug,  the  capsule 
being  completely  filled,  in  the  case  of  the  smaller  quantity,  with  sugar  of  milk. 
Thus  in  the  first  size  the  capsule  containing  one  grain  of  the  drug  contains  two 
grains  of  sugar  of  milk,  and  that  containing  two  grains  of  the  drug  being  filled 
out  with  one  grain  of  sugar  of  milk. 
We  have  been  led  to  put  up  quinine  and  cinchonidia  in  this  form  through 
the  great  popularity  which  our  Soft  Elastic  Liquid-Filled  Capsules  have  achieved 
in  the  short  period  since  our  introduction  of  them.  For  those  who  are  familiar 
with  the  latter,  the  Quinine  and  Cinchonidia-Filled  Soft  Elastic  Capsules  will 
require  no  commendation. 
An  additional  advantage  possessed  by  these  capsules  is  the  fact  that  the 
drug  entering  into  each  one  of  them  is  separately  weighed  before  being  encap- 
suled.  We  are  thus  enabled  to  guarantee  the  absolute  correctness  of  the  amount 
claimed  on  the  label. 
These  capsules  are  put  up  in  boxes  containing  1  doz.,  2  doz.,  3  doz.,  and  100 
in  each.  Owing  to  their  soft  nature,  to  put  them  up  in  bottles,  after  the  manner 
of  pills  or  hard  capsules,  would  be  to  expose  them  to  the  risk  of  molding  and 
to  distort  their  shape. 
Both  the  manufacture  and  the  packing  of  these  capsules  require  especial 
care.  We,  therefore,  in  order  to  guard  against  the  imposition  of  imitators,  have 
sealed  each  box  put  up  by  us,  and  disclaim  responsibility  for  any  which  are 
taken  from  a  box  the  seal  of  which  has  been  broken  prior  to  its  coming  into 
the  purchaser's  possession. 
We  respectfully  ask  a  trial  of  these  capsules  at  the  hands  of  the  profession, 
feeling  confident  of  a  favorable  judgement. 
PARKE,  DAVIS  &  CO., 
Manufacturing  Chemists, 
DETROIT,  MICHIGAN. 
