482 
Analysis  of  Phlox  Carolina. 
Am.  Jour.  Pharm. 
Oct.,  1886. 
I  regret  that  the  results  of  an  ultimate  analysis  could  not  be 
included  in  this  description.  This,  however,  is  reserved  for  another 
paper,  because  there  have  been  discovered  during  the  past  year,  in 
the  same  laboratory,  two  other  new  crystalline  compounds  which 
closely  resemble  this;  one,  in  a  bark  from  Honduras,  by  Mr.  F. 
Holberg,  for  an  account  of  which  see  Amer.  Jour.  Pharmacy, 
May,  1886.  The  other  was  likewise  discovered  in  a  Honduras  drug 
by  Miss  Helen  C.  D.  Abbott,  and  an  account  of  it  read  by  her  before 
the  American  Association  for  the  Advancement  of  Science  at  its 
recent  meeting  in  Buffalo.  These  three  interesting  compounds  will 
be  made  the  subject  of  another  paper.  . 
The  ether  soluble  portion  contained  a  small  quantity  of  the  red 
coloring  matter  which  was  found  with  the  camphor.  On  evaporating 
the  ethereal  solution  to  dryness  and  treating  with  water,  a  solution 
was  obtained  which  gave  no  indication  of  the  presence  of  alkaloids  or 
glucosides,  but,  on  evaporation  over  sulphuric  acid,  a  minute  quantity 
of  crystals  formed  which  were  not  further  examined. 
That  portion  of  the  original  drug  which  dissolved  in  absolute 
alcohol  was  found,  after  evaporating  the  solvent,  to  be  completely 
soluble  in  water.  It  amounted  to  9*96  per  cent.,  of  which  1*82  per 
cent,  was  tannin,  1*05  per  cent,  sugar  and  7*09  per  cent,  undeter- 
mined. A  separate  determination  of  the  tannin  in  the  original  drug 
by  the  gelatin  and  alum  process  confirmed  the  estimation  of  that 
substance.  This  tannin  was  found  to  be  of  the  variety  which  forms 
with  salts  of  iron  a  green  color.  The  remaining  solvents  did  not 
dissolve  anything  of  especial  interest. 
Fifty  grams  of  the  original  drug  were  distilled  with  milk  of  lime, 
but  tests  applied  to  the  distillate  showed  the  absence  of  a  volatile 
alkaloid. 
Another  quantity  distilled  with  dilute  sulphuric  acid  furnished  a 
distillate  acid  in  reaction  and  unaffected  by  barium  chloride  or  neutral 
lead  acetate,  but  forming  a  white  precipitate  with  basic  lead  acetate. 
The  remainder  of  the  distillate  was  treated  with  slight  excess  of  pure 
barium  carbonate,  evaporated  to  small  bulk  and  set  aside  over  sul- 
phuric acid  to  crystallize.  The  result  was  a  small  amount  of  crystals 
of  the  barium  salt,  which,  on  treatment  with  concentrated  sulphuric 
acid,  gave  an  odor  strongly  resembling  butyric  acid.  This  was  not 
further  examined  as  the  amount  present  could  not  be  considered  more 
than  a  trace. 
