AlE^!imarm'}    Practical  Notes  from  Various  Sources.  599 
formation  of  o-o-p-trichlor phenol.  This  reaction  was  previously  de- 
scribed by  W.  Dianin  (Ibid.  1880,  p.  2403);  at  the  end  of  the  reac- 
tion the  chlorophenols  exist  as  calcium  compounds,  from  which  they 
are  liberated  by  hydrochloric  acid,  and  may  then  be  separated  by 
distillation  with  steam.  Dianin  stated  also  that  trichlorphenol  checks 
fermentation  more  energetically  than  carbolic  acid,  and  that  for  this 
reason  a  mixture  of  phenol  and  chlorinated  lime  is  far  superior  for 
the  dressing  of  suppurating  wounds  than  a  solution  of  either  one  of 
these  substances.    (See  Amer.  Jour.  Phar.,  1884,  p.  51.) 
For  the  extemporaneous  preparation  of  trichlorphenol,  Prof. 
Bartholow,  recommends  (Coll.  and  Clin,  Rec>  1886,  p.  216),  mixing 
and  then  filtering  one  part  of  a  4  per  cent,  solution  of  carbolic  acid 
and  five  parts  saturated  solution  of  chlorinated  lime.  Obviously, 
the  liquid  contains  the  new  compound  in  combination  with  calcium. 
Zinc  salicylate  is  coming  into  use  in  medicine,  and  is  prescribed  in 
the  form  of  solution  in  water.  Of  two  commercial  samples  examined 
by  F.  H.  Alcock  (Phar.  Jour,  and  Trans.,  Sept.  18,  1886,  p.  226), 
one  was  fairly  soluble  in  warm  water,  crystallized  on  cooling  in  long 
needles,  and  when  incinerated  at  as  low  a  temperature  as  possible, 
emitted  an  agreeable  odor,  assumed  a  pink  color,  and  finally  left  20  8 
per  cent,  of  oxide  of  zinc.  The  other  sample  was  less  freely  soluble 
in  warm  water,  leaving  behind  a  white  powder,  the  filtrate  crystal- 
lizing in  needles ;  on  incineration  the  salt  did  not  give  off  the  same 
peculiar  odor,  became  black,  and  left  25' 3  per  cent,  of  zinc  oxide. 
For  the  preparation  of  this  and  other  salicylates,  see  Am.  Jour.  Phar., 
1886,  p.  246. 
Bismuth  oxyiodide  is  regarded  by  Dr.  A.  Sidney  Reynolds  (Med. 
News.,  Oct.  9,  1886),  as  being  very  valuable  in  the  treatment  of  chronic 
ulceration ;  he  states  that  the  salt  will  control  inflammation,  allay 
irritation,  suppress  suppuration,  promote  granulation  and  induce  cica- 
trization. He  has  also  employed  it  internally  in  doses  of  5  to  10 
grains. 
When  a  solution  of  bismuth  subnitrate  in  nitric  or  in  hydrochloric 
.acid  is  diluted  with  water  as  far  as  possible,  and  is  then  added  gradu- 
ally and  with  continual  stirring  to  a  solution  of  potassium  iodide,  a 
brown  precipitate  is  produced,  which  on  dilution  with  water  turns 
yellowish-red,  and  on  drying  yields  a  bright,  brick-red  powder,  con- 
sisting in  the  main  of  BiOI,  but  mixed  with  variable  proportions  of 
subnitrate  or  oxychloride.    To  obtain  the  oxyiodide  pure,  the  brown 
