314 
Studies  in  Plant  Mutation. 
Am.  Jour.  Pharm. 
July,  1906. 
composites  with  their  highly  developed  stable  forms  are  favored, 
while  the  species  of  Cactus  is  hindered. 
The  favoring  action  of  aconitine  in  almost  every  case,  except  with 
Erodium  and  the  Cactus,  also  appears. 
The  next  series  of  tests  with  related  groups  were  with  the  families 
included  by  Engler  and  Prantl  in  the  Tubuliflorae. 
Strychnine. 
Brucine. 
Atropine. 
Digitaliu. 
Quinine. 
Morphine. 
Aconitine. 
Hydrophyllacese  : 
•*  (3)  
(4)  
0 
IOOO 
IOOO 
IOOO 
0 
IOOO 
106 
IOOO 
0 
IOOO 
IOOO 
IOOO 
IOOO 
(control  1000.) 
Polemoniaceae : 
Gilia  (i)  
"  (3)  
IOOO 
IOOO 
IOOO 
IOOO 
IOOO 
IOOO 
IOOO 
IOOO 
IOOO 
IOOO 
IOOO 
IOOO 
(control  1000.) 
Iyabiatse  : 
IOOO 
100 
0 
100 
100 
100 
Solanaceae : 
120 
113 
26 
Scrophulariaceae  : 
Pentstemon  
25 
25 
75 
175 
50 
100 
275 
Verbenaceae  : 
IOOO 
IOOO 
IOOO 
75 
125 
IOOO 
Borraginac 'ae  : 
IOOO 
IOOO 
IOOO 
IOOO 
100 
100 
100 
100 
166 
IOOO 
IOOO 
IOOO 
With  Gilia  and  Phacelia,  in  the  seven  species  tried,  the  activity  of 
the  extracts  makes  any  comparison  of  the  effect  of  the  alkaloids 
impossible. 
With  the  others  of  this  group  the  favoring  action  of  strychnine 
and,  in  a  less  degree,  of  brucine  is  marked. 
The  hindering  action  of  atropine,  an  alkaloid  of  the  Solanaceae, 
with  Quincula  forms  the  only  exception  to  the  rule  that  the  alkaloid 
of  a  family  favors  the  diastase  action  of  the  species  of  that  family, 
and  Quincula  is  exceedingly  variable. 
Atropine  aids  with  Verbena  and  inhibits  with  the  closely  related 
Salvia,  while  with  the  Borages  it  is  indifferent. 
The  31  species  tested,  representing  24  genera  and  20  families,  show 
conclusively  that  the  action  of  alkaloids  with  the  diastase  varies  ac- 
cording to  the  alkaloid  and  the  family.    The  tests,  fragmentary  and 
