12 
Sidphocarholic  Acid,  etc. 
j  Am.  Jour.  Pharm. 
I     Jan.  2,  1871. 
valent  of  carbolic  acid  with  one,  two,  four,  five,  six  and  eight  equiva- 
lents of  sulphuric  acid. 
From  the  first  to  the  fifth  mixture,  I  remarked  that  precipitate  a 
kept  steadily  increasing  in  proportion,  and  remained  stationary  after- 
wards. I  noticed  also  that  all  mixtures  containing  less  than  six 
equivalents  of  sulphuric  to  one  of  carbolic  acid  had  more  or  less  of  a 
carbolic  smell,  while  in  this  last  all  odor  had  completely  disappeared. 
From  these  two  facts,  I  think  I  can  safely  conclude  that  it  requires  six 
equivalents  of  sulphuric  acid  to  transform  completely  one  equivalent 
of  carbolic  acid  into  sulphocarbolic  acid. 
Not  wishing  to  make  this  communication  too  lengthy,  I  shall 
describe  here  only  the  examination  of  the  1st,  2nd  and  5th  mixtures, 
the  most  important. 
The  first,  proposed  by  Mr.  T.  Omar  Guy,  was  composed  of  one 
equivalent  of  carbolic  acid  and  less  than  one  equivalent  of  sulphuric 
acid,  or  in  weight  94  grains  of  the  former  and  49  of  the  latter ;  it 
gave  for  100  grains  when  treated  by  35  grains  carbonate  baryta  : 
Precipitate  a,  .  .  .  .37  grs. 
"6,  .  .  .  .  1 
C,  .  .  .  .  ±2 
The  second,  viz.,  one  equivalent  carbolic  acid  and  two  equivalents 
sulphuric  acid,  or  in  weight  94  grs.  carbolic,  98  grs.  sulphuric  acid> 
gave  for  100  grains,  after  saturation  by  50  grs.  carbonate  baryta : 
Precipitate  a,  .  .  .  .49  grs. 
h,  .  .  .  .      2  " 
"         c?,  .  .  .  .  9 
The  fifth,  containing  one  equivalent  of  carbolic  acid  and  six  of  sul- 
phuric acid,  or  in  weight  188  grs.  carbolic  acid  and  607  grs.  sulphuric 
acid,  79  p.  c.  was  made  without  heat.  After  two  hours  contact  the 
mixture  presented  no  carbolic  smell  whatever. 
One  hundred  grains  of  it  were  treated  by  140  grs.  carbonate 
baryta,  and  gave : 
Precipitate  a,  .  .  .  .41  grs. 
6,  .  .  .  .    32  " 
"        c,  .  .  .  .  92 
As  I  remarked  before,  this  is  the  proportion  in  which  the  two  acids 
are  to  be  mixed,  in  order  to  transform  all  the  carbolic  acid  into  sul- 
phocarbolic acid. 
