220 
Ferrated  Elixir  of  Cinchona. 
/  Am.  Jour.  Phakm. 
t    May  1, 1871. 
Agitate  this  mixture  with  moist  freshly  precipitated  hjdrated  ses- 
quioxide  of  iron  (well  washed),  prepared  from  an  aqueous  solution  of 
the  sesquichloride,  for  three  or  four  days,  or  until  a  portion  filtered 
off  shows  no  reaction  with  the  tincture  of  chloride  of  iron.  Filter, 
and  dissolve  in  it,  without  heat,  two  and  a  half  pounds  (av.)  sugar. 
Add  1024  grs.  pyrophosphate  of  iron,  previously  dissolved  in  a  small 
portion  of  water,  and  make  up  the  measure  of  one  gallon,  if  neces- 
sary, by  the  addition  of  water.  If  a  more  reddish  color  is  wanted, 
use  a  few  grains  of  soluble  citrate  of  iron. 
The  elixir  thus  prepared  will  keep  well  in  color,  and  has  a  resem- 
blance to  the  article  extensively  advertised  under  the  same  name. 
If  the  cinchona  bark  contains  8  per  ct.  of  alkaloids,  and  supposing 
th#  bark  to  be  entirely  exhausted,  one  gallon  of  elixir  prepared 
£iccording  to  the  above  formula  would  contain  about  60  grains  of 
alkaloids,  or  nearly  half  a  grain  to  the  fluidounce.  Cinchona  bark^ 
however,  cannot  be  completely  exhausted  by  weak  alcohol,*  and  after 
the  treatment  of  the  resulting  tincture  with  hydrated  sesquioxide  of 
iron,  the  natural  combination  of  the  cinchona  alkaloids  is  broken  up, 
and  nothing  of  medicinal  value  is  retained  by  the  liquid  except  the 
alkaloids,  t  The  aroraatics  used  in  most  of  the  formulas  I  believe  add 
comparatively  little  to  the  medicinal  virtues  of  this  preparation,  which 
aims,  ostensibly,  to  unite  the  tonic  properties  of  cinchona  and  iron. 
These  considerations  induced  me  to  take  advantage  of  the  excellent 
combination  of  aromatics  with  calisaya  bark,  which  was  suggested  by 
Dr.  Squibb, J  and  has  met  with  great  favor  by  the  medical  corps  of 
the  U.  S.  Army.  Accordingly,  I  have  dispensed  for  the  last  five 
years  a  ferrated  elixir  of  calisaya  made  by  the  following  formula,  and 
manipulated  as  follows: 
1.  Triturate  magnes.  carbon,  ^ss.  first  with  the  following  volatile 
oils:  0].  aurantii  m  xx,  ol.  anisi  m  xv,  ol.  coriandri  and  cinnam.  aa 
m  10,  ol.  carvi  m  v ;  then,  with  a  mixture  of  2  oz.  alcohol  and  14  oz. 
water,  throw  upon  a  filter  and  wash  with  water  until  the  filtrate  meas- 
ures 3J  pints. 
2.  Mix  tinct.  cardam.  (simpl.)  f^ij,  tinct.  zingib.  and  calami  aa  f^i, 
iilcohol  Oj,  and  add  syrup,  simpl.  Oj. 
3.  Dissolve  unbleached  quinia  3iss,  with  acid.  citr.  ^ijss,  in  alcoh. 
dilut.  f^iv. 
*  Am.  Jour.  Fh.  1861, 194.  f  Ibid.  1861,  304.    %  Ibid.  1863^  230. 
