Am.  Jour.  Pharm.  1 
November,  1905.  J 
Chemical  Materia  Medica. 
545 
Potassium  bromide;  by  Balard  in  1826. 
Bromine;  discovered  by  Balard  in  Montpelier,  France,  in  1826. 
Iodoform;  produced  by  Serullas  in  1822,  but  not  introduced  into 
the  materica  medica  until  about  1837. 
Santonin;  discovered  in  1830,  independently  of  each  other,  by 
two  German  apothecaries,  Kahler  in  Dusseldorf  and  Alms  in  Meck- 
lenburg. 
Atropine;  isolated  by  Meins  in  183 1. 
Codeine;  by  Robiquet  in  1832. 
Phenol;  discovered  by  Runge,  in  coal  tar,  in  1834. 
Salicylic  acid;  in  1839,  Kolbe,  in  1873,  introduced  it  as  an  anti- 
septic. 
Chloral  hydrate;  discovered  in  1832  by  Liebig.  Was  introduced 
as  a  medicine  by  Liebreich  in  1869. 
Chloroform  ;  discovered  by  Liebig,  and  also  by  Soubeiran  in  1 83 1. 
Introduced  into  medicine  by  Simpson  in  1847. 
Theobromine ;  isolated  from  the  seeds  of  Theobroma  cacao  in 
1 84 1  by  Woskresensky. 
Collodion;  introduced  in  1853  by  Maynard  and  Bigelow. 
Physostigmine ;  by  Jobst  and  Hesse  in  1864. 
Resorcin;  by  Hlasiwetz  in  1864. 
Cocaine;  isolated  by  Gaedeke  in  1864.  Introduced  into  medicine 
in  1884  by  Roller. 
Formaldehyde ;  discovered  by  A.  W.  Hoffman  in  1867. 
Pilocarpine;  Gerrard  and  Hardy  in  1875. 
§odium  salicylate  ;  made  synthetically  by  Kolbe's  process  in  1875. 
Naphthol;  1881. 
Apomorphine  hydrochlorate ;  used  in  1882.    The  free  base  had 
been  discovered  in  1869  by  Matthiessen  and  Wright. 
Antipyrine ;  discovered  by  Knorr  in  1884. 
Acetanilid ;  discovered  by  Gerhard,  has  been  in  use  since  1886. 
Phenacetine;  1887. 
Saccharin;  1887. 
Sulfonal ;  discovered  by  Baumann  in  1888. 
Trional ;  1893.  M.  I.  Wilbert. 
