Am.  Jour  Pharm. ) 
Mar.,  1879.  / 
Quinia  Test. 
the  admixture  should  amount  to  2  per  cent. ;  but  the  admixture  not 
only  retards  the  formation  of  crystals,  but,  within  certain  limits,  pre- 
vents it  entirely.  With  such  an  admixture,  which  may  even  be  increased 
to  3  per  cent.,  results  were  obtained  agreeing  exactly  with  Fig.  1  of 
Godeffroy,  obtained  from  pure  (?)  sulphate  of  quinia.  If  the  said 
admixture  is  increased  to  5  per  cent,  a  copious  separation  of  minute 
drops  is  observed  at  the  first  moment,  but  above  this  percentage  the 
sulphocyanides  crystallize  rapidly. 
From  this  it  follows  that  the  test  in  question  will  indicate  in  sulphate 
of  quinia  an  admixture  of  at  least  1  per  cent,  of  the  sulphates  of 
cinchonia  and  quinidia,  and  5  per  cent,  of  the  sulphates  of  cinchonidia 
and  homo-cinchonidia,  provided  that  the  sulution  of  the  latter  is  pre- 
pared in  the  manner  indicated  above.  If  the  solution  is  prepared  by  a 
different  mode,  whether  as  directed  by  Schrage  or  by  Kerner,  the  deli- 
cacy of  the  test,  which  I  cannot  regard  as  being  of  much  practical 
value,  is  materially  impaired. 
QUINIA  TEST. 
By  O.  Hesse. 
Translated  from  Archiv  der  Pharmacie>  December,  1878,  by  P.  H.  Dilg,  Ph.G. 
During  several  months  past,  I  have  exclusively  tested  sulphate  of 
quinia  by  the  following  method,  which  may  also  be  applied,  properly 
modified,  to  other  salts  of  quinia.  My  test  is  based  on  the  following 
facts : 
1st.  That  sulphate  of  quinia  is  sparingly  soluble  in  water  at  500  to 
6o°C,  while  the  other  sulphates  are  readily  dissolved  without  decom- 
position. 
2d.  That  when  the  cooled  solution,  after  being  supersaturated  with 
ammonia,  is  shaken  with  just  sufficient  ether  for  dissolving  the  quinia, 
this  quantity  will  be  insufficient  for  the  other  alkaloids  if  present  to  a 
certain  extent. 
To  exe:utethe  test  I  employ  a  tube  which,  for  convenience  may  be 
termed  "  Quininometer."  The  dimensions  which-  have  proved  satis- 
factory in  practice  are  10  to  1 1  mm.  in  diameter  and  120  mm.  in 
height.  It  is  marked  at  B  and  C,  the  space  A  to  B  being  of  5  cc,  and 
B  to  C  of  1  cc.  capacity. 
0*5  gram  sulphate  of  quinia  is  well  shaken  in  a  large  test  tube  with 
