154         Minutes  of  the  Pharmaceutical  Meeting.  { ^d™^™ 
Cinchona  Alkaloids  in  their  Natural  Combination.  —  According  to  De  Vrijr 
the  alkaloids  exist  in  cinchona  barks  in  combination  with  cinchotannic  acid,  while 
kinic  acid  is  present  in  the  free  state.  It  is  owing  to  the  latter  acid  that  a  portion 
of  the  cinchotannates  are  soluble  in  cold  water.  The  cinchotannates  of  the  dex- 
trogyre  alkaloids  are  more  freely  soluble  than  those  of  the  levogyre  alkaloids  — Jour, 
de  Phar.  et  de  Chim.,  Sept.,  1878,  p.  324. 
Quinia  Test — C.  Rump  prefers  the  following  modification  of  Hesse's  test  (see- 
page 135):  0*5  gram  of  quinia  sulphate  is  put  into  an  ordinary  test  tube;  10  grams 
of  distilled  water  are  added,  the  test  tube  immersed  in  hot  water  for  some  time,  and 
after  the  contents  have  again  cooled  5  grams  of  the  liquid  are  filtered  into  another 
test  tube,  and  to  this  is  added  1  gram  of  ether  and  from  3  to  5  drops  of  ammonia 
water,  after  which  the  tube  is  corked  and  set  aside.  Measuring  the  ether  is  less 
accurate  than  weighing,  and  1  cc.  of  ether  is  insufficient  for  the  purpose. — Phar* 
Zeitung,  1879,  No.  9. 
Villate's  Mixture  in  the  Treatment  of  Sinuses. — A  report  from  the  Charity 
Hospital,  New  York,  in  the  New  York  "  Medical  Journal,"  states  that  several  deep 
sinuses  have  recently  been  under  treatment  in  the  surgical  service,  in  which  no 
necrosed  bone  could  be  found,  but  which  proved  intractable  to  heal.  Villate's  mix- 
ture was  tried,  first  of  half  strength.  In  some  of  the  cases  it  proved  of  value,  in 
others  it  failed  partially  or  completely.  The  case  in  which  it  proved  of  most  service 
was  one  of  deep  sinus  in  the  neighborhood  of  the  hip  joint.  The  original  composi- 
tion of  the  mixture  was — 
R     Liq.  plumbi  subacet  ,  .  .  .  ^i    30  I 
Zinci  sulph.  cryst  ,  | 
Cupri  sulph.  cryst.,  .  .  ad  3SS  2 
Aceti  vini  albi,  .  .  fl.  ^viss    26  | 
The  mixture  was  injected  once  a  day,  and  proved  a  more  satisfactory  application! 
than  any  other.  Some  patients  complained  of  severe  pain,  others  felt  but  slight 
inconvenience  from  it. —  Ohio  Med.  Recorder. 
Formula  for  Paresi's  Hemostatic  Collodion. — 
Officinal  collodion,  ....  100 
Carbolic  acid  (pure),       .  .  .  .10 
Tannic  acid,  .  .  .  .  .5 
Benzoic  acid,  .....  3 
M.  secund.  art. — Ibid.,  from  IS  Union  Medicate. 
MINUTES  OF  THE  PHARMACEUTICAL  MEETING. 
Philadelphia,  February  18th,  1879. 
The  fifth  of  the  present  series  of  pharmaceutical  meetings  was  called  to  order  by 
Vice-President  Chas.  Bullock ;   the  minutes  of  the  last  meeting  were  read  and 
approved. 
