30O  Tully  s  Powder,  {^^igf* 
freely  soluble  in  alcohol  and  water,  insoluble  in  ether  and  chloroform. 
With  strong  sulphuric  acid  it  produces  an  orange-red  coloration  chang- 
ing to  brown. 
The  presence  of  starch,  sugar,  albumen,  resin  and  pectic  compounds 
was  also  incidentally  noticed. 
TULLY'S  POWDER. 
Manlius,  N.  Y.,  May  12th,  1879. 
Editor  of  the  American  Journal  of  Pharmacy : 
I  was  a  private  pupil  of  Dr-  William  Tully  at  New  Haven,  Conn., 
in  the  years  1846,  1847,  1848,  and  personally  know  that  the  formula 
given  on  page  230,  May  number  of  the  "  American  Journal  of  Phar- 
macy," is  the  one  he  commonly  employed,  except  that  instead  of  31 
he  wrote  £j.  The  whole  amount  of  the  three  substances  added  to  the 
morphia  is  a  drachm.1  Although  commonly  using  the  sulphate  of 
morphia  in  this  powder,  Dr.  Tully  considered  the  acetate  or  hydro- 
chlorate  of  morphia  equally  advantageous.  He  was  very  particular  to 
direct  that  the  ingredients  should  be  thoroughly  mixed  by  passing  them 
several  times  through  a  sieve  after  they  had  been  incorporated  in  a 
mortar.  I  may  say  that  I  have  used  Tully  Powder  (as  it  is  called  in 
this  vicinity)  largely  in  my  medical  practice,  and  have  been  well  satis- 
fied with  its  diaphoretic  qualities.  It  has  this  advantage  over  Dover's 
Powder,  that  it  is  very  much  less  liable  to  produce  nausea,  and  that, 
except  to  the  few  who  have  a  decided  distaste  for  camphor,  it  is  much 
more  palatable  than  Dover's  Powder.     Children  take  it  very  readily. 
No  doubt  the  substitution  of  precipitated  calcium  carbonate,  for  pre- 
pared chalk,  results  in  a  somewhat  hondsome  powder  and  probably  does 
not  change  the  medicinal  effect  of  the  combination. 
Tully  powder  should  be  kept  in  a  well-stopped  bottle  and  in  a  uni- 
form (rather  low)  temperature,  to  prevent  the  sublimation  of  some  of 
the  camphor  on  the  sides  of  the  bottle.  Of  course,  doses  of  it,  if  long 
left  in  paper,  are  liable  to  lose  the  greater  part  of  the  camphor. 
I  hope  to  see  it  introduced  into  the  next  U.  S.  Pharmacopoeia,  under 
the  name  of  pulvis  morphiae  comp.,  or,  as  Dr.  Tully  often  prescribed 
it,  under  the  name  of  pulvis  camphorae  comp.,  this  latter  designation 
1  Mr.  Wood  has  also  called  our  attention  to  the  typographical  error  alluded  to 
above. — Editor. 
