8  Ejctractum  Clmicifugce  Jhluidum.  {^'^'ianl'im^'''^' 
Formula  No.  4 :  Cimicifuga  in  No.  60  powder,  8  ounces  av. ;  al- 
cohol, 3  parts;  water,  1  part,  sufficient  to  make  8  fluid-ounces. 
Moisten  tbe  powder  with  2  fluid-ounces  of  the  menstruum. 
Pack  firmly  in  a  cylindrical  percolator ;  then  add  enough  menstruum 
to  saturate  the  powder  and  have  a  stratum  above  it;  when  the  liquid 
begins  to  drop  from  the  percolator,  close  the  lower  orifice  and  macerate 
for  forty-eight  hours.  Then  allow  the  percolation  to  proceed,  adding 
menstruum  until  the  cimicifuga  powder-is  exhausted.  Reserve  the 
first  six  fluid-ounces,  distil  off  the  alcohol  from  the  remainder,  and 
evaporate  the  residue  to  a  soft  extract ;  dissolve  this  in  the  reserved 
portion  and  add  enough  menstruum  to  make  eight  fluid-ounces. 
In  making  these  experiments  the  alcohol  was  recovered  by  the  use 
of  the  still,  and  after  having  ascertained  its  specific  gravity,  converted 
into  diluted  alcohol. 
The  making  of  fluid  extracts  is  not  a  difficult  operation  in  the 
hands  of  the  practical  pharmacist.  It  cannot  be  too  strongly  urged 
that  a  druggist  should  make  his  own  fluid  extracts.  It  is  in  these  more 
especially,  that  manufacturing  pharmacists  have  almost  a  monopoly, 
and  will  continue  so  to  have  as  long  as  the  drugman  is  disinclined  to 
help  and  work  for  his  own  individual  interest.  The  making  of  these  give 
him,  1st,  confidence  in  his  own  ability;  2d,  practical  knowledge  which 
he  cannot  know  or  remeuiber  as  well,  simply  from  books  ;  3rd,  assur- 
ance that  his  extracts  are  not  only  what  he  represents  them  to  be,  but 
that  none  are  better,  if  any  are  as  good;  4th,  respect  and  confidence 
from  the  physician,  who  must  needs  feel  that  such  a  druggist  is 
progressive,  and  trying  to  keep  up  the  advance  of  pharmacy. 
On  examination  of  the  different  residues  it  was  found  that  the  one 
in  which  three  parts  of  alcohol  and  one  of  water,  as  the  menstruum, 
was  used  was  entirely  exhausted;  the  extract  was  of  a  very  good 
quality,  if  not  superior  to  the  one  in  which  alcohol  was  used  as  the 
menstruum. 
Poisoning'  witli  I  ol. — Pallin  gives  an  account  of  a  case  of  necrosis  of 
the  clavicle  in  which  an  operation  was  performed,  and  seventy-five  grains  of  iodol 
were  applied  to  the  wound.  During  the  evening  of  the  same  day  the  patient  be- 
came delirious,  and  on  the  following  day  his  temperature  whs  102.2°  F.,  his  pulse 
was  136,  small  and  irregular,  and  he  vomited  and  was  apathetic.  The  urine 
showed  traces  of  albumen  and  a  weak  iodine  reaction.  Although  the  dressing 
was  changed  at  once,  all  the  iodol  being  washed  out  of  the  wound  and  bismuth 
applied  in  its  place,  the  symptoms  of  poisoning  Jasted  four  days  longer,  and  for 
a  fortnight  iodine  was  to  be  recognized  in  the  urine. — N.  Y.  Med.  Jour. 
