Am-  Jour.  Pharm. 
Feb., 1888. 
Emulsion  of  Terebene. 
69 
large  quantities  of  powdered  acacia,  with  the  loss  of  a  varying  per 
cent,  of  the  volatile  liquid  emulsified,  incident  to  the  long  trituration 
necessary  to  suspend  it.  Even  w^hen  finished  they  are  prone  to  sepa- 
rate. We  find  this  especially  the  case  with  sucli  liquids  as  ether, 
•    chloroform,  terebene,  etc. 
Numerous  expedients  have  been  suggested,  but  each  in  turn,  have 
failed  to  come  up  to  the  sanguine  hopes  of  their  proposers.  Taking 
advantage  of  the  great  emulsionizing  properties  of  milk,  the  writer 
has  advocated,  for  some  time,  the  giving  of  these  and  similar  liquids 
in  that  natural  emulsion,  with  each  dose,  and  the  results  obtained  have 
been  most  satisfactory.  The  advantages  are  readily  apparent ;  first, 
in  the  accuracy  of  the  dose  since  none  of  the  liquid  can  be  lost  by 
volatilization  as  in  the  preparation  of  emulsions,  and,  second,  in  its 
acceptability  to  the  patient. 
As  a  remedy  in  the  treatment  of  certain  throat  affections,  terebene 
has,  in  the  last  few  years,  attained  considerable  prominence  in  medical 
circles,  but  its  employment  has  been  restricted  on  account  of  the  im- 
possibility of  obtaining  an  emulsion  with  it,  and  recourse  was  then 
had  to  the  simpler  method  of  giving  in  capsules  or  dropping  on  sugar 
and  dissolving  in  the  mouth,  and  this  is  the  mode  of  administration 
in  general  use  at  present. 
This  expedient,  however,  is  a  very  unsatisfactor}^  one,  and  the 
writer  here  gives  a  new  process  for  the  emulsion,  based  upon  the  fact 
that  terebene  is  readily  emulsionized,  if  previously  mixed  with  an 
equal  volume  of  cotton-seed  oil.    The  formula  used  is  as  follows  : 
Take  of 
Terebene  
01.  gossyp.  sem  ..aa  n\^.  clx. 
Palv.  acacife   5  vj. 
Pulv.  sacchari   ^  ij. 
Aqusd  q.  s.  fiat   iv. 
Mix. 
Dose  :  1  to  2  teaspoonfuls  (=10-20  drops). 
I  he  product  is  a  milk-white,  perfectly  suspended  liquid,  having  the 
odor,  and  bitter,  turpentine-like  taste  of  terebene,  and  is  miscible  with 
water,  without  separation. 
This  method,  of  previously  admixing  with  cotton-seed  oil,  is  very 
useful  in  suspending  volatile  oils,  especially  the  oils  of  gaultheria  and 
eucalyptus,  which  have  come  into  such  general  use  within  the  past 
year,  and  it  is  more  economical,  in  that  a  much  less  quantity  of  acacia 
