74 
Fluid  Extract  of  Yerba  Santa.  {^FeT'iS.^''"'" 
covered  and  the  contents  macerated  for  48  hours.  At  the  expiration 
of  this  time,  the  percolation  was  allowed  to  proceed  until  the  drug 
was  exhausted.  The  first  6f  fluidounces  of  the  percolate  were  re- 
served, and  the  remainder  evaporated  to  a  soft  extract  and  dissolved 
in  the  reserve  portion,  adding  sufficient  diluted  alcohol  to  make  the 
finished  product  measure  8  fluidounces.  This  menstruum  was  not  a 
good  one.  The  extract  was  not  clear  and  a  heavy  deposit  took 
place. 
In  No.  2  a  menstruum  of  2  parts  alcohol  and  1  part  of  water  was 
used.  The  manipulations  mth  this  and  the  subsequent  ones  were  as 
in  the  preceding  one.  A  better  product  was  obtained  by  the  use  of 
alcohol  and  water  in  this  proportion.  It  was  not,  however,  a  satisfac- 
tory product,  as  there  was  a  considerable  deposit  on  allowing  it  to 
stand. 
No.  3,  in  which  3  parts  alcohol  and  1  part  water  were  used  as  a 
menstruum,  proved  to  be  the  best  of  the  lot.  A  very  good  fluid  ex- 
tract was  obtained  which  remains  clear  with  only  a  slight  deposit  after 
allowing  it  to  stand  undisturbed  more  than  two  months. 
In  No.  4  the  same  menstruum,  i.  e.,  diluted  alcohol,  as  in  No.  1, 
was  used,  except  that  10  per  cent,  of  glycerin  was  added  to  the  first 
8  fluidounces  of  menstruum  used.  A  very  unsatisfactory  product 
resulted  from  the  use  of  the  glycerin ;  the  deposit  being  greater  than 
in  No.  1. 
FLUID  EXTEACT  OF  YERBA  SANTA  (ERIODICTYON 
GLUTINOSUM). 
Contribution  from,  the  Pharmaceutical  Laboratory,  Philadelphia  College  of 
Pharmacy. 
By  F.  B.  Quackenbush. 
Read  at  the  Pharmaceutical  Meeting,  January  17. 
A  formida  for  the  above  extract  having  been  desired^  the  following 
experiments  were  undertaken  with  the  view  of  determining  the  best 
menstruum  to  secure  permanency  in  the  fluid  extract^  and  thorough 
exhaustion  of  the  drug.  The  herb  of  Eriodictyon  glutinosum,  or  as  it 
is  sometimes  called,  Eriodictyon  californicum,  was  used  in  these  ex- 
periments. It  is  non-officinal,  and  no  formula  is  given  in  the  dispen- 
satories for  its  preparation,  and  as  one  of  the  objects  was  to  find  the 
